(E)-1,4-Bis(4-chlorophenyl)but-2-ene-1,4-dione CAS 5465-37-2

Purity 97%+In StockPharmaceutical Standards
CAS No.5465-37-2
Molecular FormulaC16H10Cl2O2
Molecular Weight305.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-1,4-Bis(4-chlorophenyl)but-2-ene-1,4-dione CAS 5465-37-2 chemical structure

Description

The occurrence of (E)-1,4-Bis(4-chlorophenyl)but-2-ene-1,4-dione is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(E)-1,4-Bis(4-chlorophenyl)but-2-ene-1,4-dione (CAS 5465-37-2), molecular formula C16H10Cl2O2 and molecular weight 305.16 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system, (E)-1,4-Bis(4-chlorophenyl)but-2-ene-1,4-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 305.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (E)-1,4-Bis(4-chlorophenyl)but-2-ene-1,4-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H10Cl2O2
Molecular Weight305.16 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Halogen ContentCl-containing

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