4,7-Dichloro-2-phenyl-quinazoline CAS 54665-92-8
| CAS No. | 54665-92-8 |
| Molecular Formula | C14H8Cl2N2 |
| Molecular Weight | 275.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,7-Dichloro-2-phenyl-quinazoline (CAS 54665-92-8) is a high-purity analytical reference standard with the molecular formula C14H8Cl2N2 and a molecular weight of 275.13 g/mol.
The molecular framework of 4,7-Dichloro-2-phenyl-quinazoline (C14H8Cl2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4,7-Dichloro-2-phenyl-quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl2N2 |
| Molecular Weight | 275.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 2,2-Dichloro-1-(4-ethoxyphenyl)cyclopropanecarboxylic acid (CAS 104023-75-8)
- 2,4-Dichloro-5-phenylquinazoline (CAS 1272356-64-5)
- 3,5-Dichloro-4-(cyclopentyloxy)benzoic acid (CAS 1272528-03-6)
- 2,3-Dichloro-6-phenylquinoxaline (CAS 1420794-75-7)
- N-(2,6-Dichloro-3-formylpyridin-4-yl)pivalamide (CAS 1569309-60-9)
- 2,6-Dichloro-3-phenylquinoxaline (CAS 76672-25-8)
- 2,6-Dichloro-4-phenylquinazoline (CAS 5185-54-6)
- 2,6-Dichloro-N-morpholinobenzamide (CAS 294849-17-5)
Recommended Standards
- 4,6-Dichloro-2-phenyl-quinazoline (CAS 54665-93-9)
- 4-Butyl-2-iodoaniline (CAS 952054-06-7)
- 4,6-Dichloro-2-(naphthalen-1-yl)pyrimidine (CAS 89517-04-4)
- 4-Chloro-2-(2-chlorophenyl)quinazoline (CAS 59455-92-4)
- 4-Ethoxy-5-isopropyl-2-methylaniline hydrochloride (CAS 473704-48-2)
- 1-(4'-Methoxy-[1,1'-biphenyl]-4-yl)pentan-1-one (CAS 56116-77-9)
- 2,4-Dimethylpent-4-en-2-ol (CAS 19781-53-4)
- 2-Methoxy-6-methylpyrazine (CAS 2882-21-5)
- 4-Methyl-2-(tributylstannyl)pyridine (CAS 301652-23-3)
- 4-[(3-Chloropropanoyl)amino]benzoic acid (CAS 19314-11-5)
- N-(3,5-Dimethylphenyl)-5-methyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (CAS 1574585-14-0)
- 4-(4-Bromo-1H-pyrazol-1-yl)-2-methylbutan-2-ol (CAS 1430727-38-0)
- 3-Bromo-5-iodopyridin-4-ol (CAS 637348-83-5)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com