Flumazenil Impurity 19 CAS 548487-68-9
| CAS No. | 548487-68-9 |
| Molecular Formula | C12H14FN3O |
| Molecular Weight | 235.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 235.26 g/mol gives Flumazenil Impurity 19 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Flumazenil Impurity 19 (CAS 548487-68-9) is a certified pharmaceutical impurity reference standard with the molecular formula C12H14FN3O and a molecular weight of 235.26 g/mol.
Flumazenil Impurity 19 (C12H14FN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Flumazenil Impurity 19 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14FN3O |
| Molecular Weight | 235.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Flumazenil Standards
- Flumazenil Impurity 13 (CAS CATO-C4X-143213)
- Flumazenil Impurity 22 (CAS 193693-31-1)
- Flumazenil Impurity 9 (CAS 5973-29-5)
- Flumazenil EP Impurity D (CAS 78755-80-3)
- Flumazenil Impurity 10 (CAS 162110-24-9)
- Flumazenil EP Impurity A (CAS 84378-44-9)
- Flumazenil Impurity 20 (CAS CATO-C4X-143220)
- Flumazenil EP Impurity E (CAS 78756-03-3)
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- 4-Amino-6-(difluoromethyl)-5-(trifluoromethyl)pyridin-3-ol (CAS 1803697-67-7)
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