5-Amino-6-chloropyrimidine-4-thiol CAS 54851-35-3
| CAS No. | 54851-35-3 |
| Molecular Formula | C4H4ClN3S |
| Molecular Weight | 161.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 161.61 g/mol gives 5-Amino-6-chloropyrimidine-4-thiol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 5-Amino-6-chloropyrimidine-4-thiol (CAS 54851-35-3), a certified reference material (molecular formula C4H4ClN3S, MW 161.61 g/mol) for analytical method development and quality control.
Owing to a nitrile group, sulfur-containing functionality, chlorine substitution, 5-Amino-6-chloropyrimidine-4-thiol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 161.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Amino-6-chloropyrimidine-4-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H4ClN3S |
| Molecular Weight | 161.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 4-Amino-6-chloropyrimidine-2-thiol (CAS 116230-29-6)
- 5-Amino-2-chloropyrimidine-4(3H)-thione (CAS 14623-59-7)
- 3-Amino-5-chloropyrazine-2(1H)-thione (CAS 1801693-88-8)
- 2-Amino-6-chloropyrimidine-4(3H)-thione (CAS 6310-02-7)
- 2-(3-Amino-4-chloro-1h-pyrazol-1-yl)ethan-1-ol (CAS 1409471-42-6)
- 4-Amino-2-chloro-3-fluorophenol (CAS 1003710-18-6)
- 2-Amino-5-chloro-4-fluorophenol (CAS 1191063-34-9)
- 3-Amino-4-chloro-2-fluorophenol (CAS 1427407-07-5)
Recommended Standards
- 4-Methyl-1,3-thiazole-5-carbonyl chloride (CAS 54237-09-1)
- 5-Methyl-1,3-thiazole-2-carbonyl chloride (CAS 61291-22-3)
- 4-Methyl-1,3-thiazole-2-carbonyl chloride (CAS 79312-42-8)
- Rivaroxaban Impurity 114 (CAS 22353-82-8)
- 2-Chloro-3-(4-(indoline-1-carbonyl)piperidin-1-yl)naphthalene-1,4-dione (CAS 685106-73-4)
- 5-Chloro-2-(3,5-dimethylphenoxy)aniline (CAS 893751-01-4)
- 2-methylpropyl N-(3-aminophenyl)carbamate (CAS 1019388-96-5)
- 3-(2-Azidoethyl)-3-methyl-3H-diazirine (CAS 1800541-83-6)
- 8-Methyl-2-oxo-2H-chromene-3-carboxylic acid (CAS 58734-32-0)
- 3-(2-methoxyphenyl)cyclobutan-1-one (CAS 335331-55-0)
- (2R,3S)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one (CAS 30825-34-4)
- 7-Chloro-2-iodoimidazo[1,2-a]pyridine (CAS 1384265-42-2)
- tert-Butyl 2-amino-6-methoxybenzoate (CAS 1533154-01-6)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
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