Quinine Bisulphate CAS 549-56-4
| CAS No. | 549-56-4 |
| Molecular Formula | C20H24N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Quinine Bisulphate.
Quinine Bisulphate (CAS 549-56-4), molecular formula C20H24N2O2H2O4S and molecular weight 422.50 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Quinine Bisulphate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 422.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Quinine Bisulphate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H24N2O2 H2O4S |
| Molecular Weight | 422.50 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Quinine Standards
- Quinine Sulfate Impurity 5 (CAS 101655-92-9)
- Quinine Impurity 1 (CAS 1092116-26-1)
- Quinine N-Oxide (CAS 109906-48-1)
- Quinine Hydrochloride (CAS 130-89-2)
- Quinine (CAS 130-95-0)
- Quinine Sulfate (500 mg) (CAS 207671-44-1)
- Quinine sulfate Impurity 6 (CAS 485-71-2)
- Quinine Sulfate - Impurity C (Sulfate Salt) (CAS 49722-46-5)
Recommended Standards
- 1-amino-3-phenylguanidine hydroiodide (CAS 56204-41-2)
- 4-Bromo-3,5-dichlorobenzene-1,2-diamine (CAS 98138-54-6)
- Tert-butyl 9-amino-3-azabicyclo[3.3.1]nonane-3-carboxylate (CAS 1198466-20-4)
- 6-(Methylthio)-9-pentyl-9H-purin-2-amine (CAS 105959-97-5)
- 3-Methoxy-1-phenyl-1H-isoindole (CAS 25365-84-8)
- Tetra-tert-butyl 2,2',2'',2'''-((((2-(tert-butoxy)-2-oxoethyl)azanediyl)bis(ethane-2,1-diyl))bis(azanetriyl))tetraacetate (CAS 280563-33-9)
- 1,3-Dimethylimidazolium Chloride (CAS 79917-88-7)
- 3-amino-1-methylpyrrolidin-2-one (CAS 119329-48-5)
- 4-Amino-3-methyl-3-(4-propylphenyl)butanoic acid (CAS 1489686-32-9)
- Tetrapeptide-3 (CAS 827306-97-8)
Why CATO?
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