2-(3-chloro-4-fluorophenyl)-1,3-thiazole-4-carboxylic acid CAS 549526-19-4

Purity 97%+In StockPharmaceutical Standards
CAS No.549526-19-4
Molecular FormulaC10H5ClFNO2S
Molecular Weight257.67 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(3-chloro-4-fluorophenyl)-1,3-thiazole-4-carboxylic acid CAS 549526-19-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 257.67 g/mol gives 2-(3-chloro-4-fluorophenyl)-1,3-thiazole-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(3-chloro-4-fluorophenyl)-1,3-thiazole-4-carboxylic acid (CAS 549526-19-4), molecular formula C10H5ClFNO2S and molecular weight 257.67 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C10H5ClFNO2S, 2-(3-chloro-4-fluorophenyl)-1,3-thiazole-4-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 257.67 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-(3-chloro-4-fluorophenyl)-1,3-thiazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H5ClFNO2S
Molecular Weight257.67 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF/Cl-containing
Nitrogen Atoms1
Sulfur Atoms1

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