(E)-3-((2-chlorobenzyl)thio)-4-(4-chlorophenyl)-5-styryl-4H-1,2,4-triazole CAS 551920-96-8
| CAS No. | 551920-96-8 |
| Molecular Formula | C23H17Cl2N3S |
| Molecular Weight | 438.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (E)-3-((2-chlorobenzyl)thio)-4-(4-chlorophenyl)-5-styryl-4H-1,2,4-triazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(E)-3-((2-chlorobenzyl)thio)-4-(4-chlorophenyl)-5-styryl-4H-1,2,4-triazole (CAS 551920-96-8), molecular formula C23H17Cl2N3S and molecular weight 438.37 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-3-((2-chlorobenzyl)thio)-4-(4-chlorophenyl)-5-styryl-4H-1,2,4-triazole (C23H17Cl2N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H17Cl2N3S |
| Molecular Weight | 438.37 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related E Standards
- 3-((4-Chlorobenzyl)thio)-5-(4,5-dihydronaphtho[1,2-b]thiophen-2-yl)-4-ethyl-4H-1,2,4-triazole (CAS 477887-85-7)
- N-(2-Chlorobenzyl)-3-(4-isobutyl-5-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinazolin-1-yl)propanamide (CAS 902973-15-3)
- 3-(2-((4-Chlorobenzyl)oxy)phenyl)-1-tosyl-1H-pyrazole (CAS 477713-44-3)
- 2-((4-Chlorobenzyl)oxy)-4-(((4-chlorophenyl)imino)methyl)-3-hydroxyisoquinolin-1(2H)-one (CAS 338419-49-1)
- 2-(5-((4-Chlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)thieno[2,3-b]quinoline (CAS 478260-37-6)
- 2-((4-Chlorobenzyl)sulfinyl)-1,1-bis(4-chlorophenyl)ethanol (CAS 252026-70-3)
- 5-(4-((4-Chlorobenzyl)oxy)phenyl)-N'-(thiophen-2-ylmethylene)-1H-pyrazole-3-carbohydrazide (CAS 634896-25-6)
- (5-((2-Chlorobenzyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl cyclopropanecarboxylate (CAS 955964-19-9)
Recommended Standards
- Upadacitinib Impurity 171 (CAS CATO-C4X-2405171)
- 4-(4-Chlorophenyl)-3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(E)-2-phenylethenyl]-4H-1,2,4-triazole (CAS 551920-94-6)
- methyl 8-{3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}octanoate (CAS 680215-99-0)
- 4-Bromo-N-cyclohexyl-N-[(4-methoxyphenyl)methyl]benzene-1-sulfonamide (CAS 1881330-21-7)
- (T-4)-Bis(8-quinolinolato-κN1,κO8)magnesium (CAS 67952-28-7)
- 2-(Chloromethyl)-5-(difluoromethyl)-1,3,4-thiadiazole (CAS 1443982-10-2)
- 2-(3-Methoxybenzo[d]isothiazol-5-yl)acetonitrile (CAS 65412-57-9)
- 2,3,5-Triiodo-pyrrole (CAS 56821-78-4)
- Cefditoren Impurity 1 (CAS 148774-47-4)
- 6alpha-Methoxymethyl Exemestane Impurity (CAS 881896-95-3)
- Fmoc-n-methyl-dl-leucine (CAS 1362858-89-6)
- (s)-2-Amino-2-(3,4-difluorophenyl)ethan-1-ol (CAS 1269935-50-3)
- (3-Cyano-2-hydroxyphenyl)trifluoroborate (CAS 2376462-72-3)
- Cycloaspeptide A (CAS 109171-13-3)
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