(E)-N-((((2-chloro-6-fluorobenzyl)oxy)imino)methyl)-3-cyano-5,7-dimethylimidazo[1,2-a]pyrimidine-2-carboxamide CAS 551921-44-9

Purity 97%+In StockPharmaceutical Standards
CAS No.551921-44-9
Molecular FormulaC18H14ClFN6O2
Molecular Weight400.79 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-N-((((2-chloro-6-fluorobenzyl)oxy)imino)methyl)-3-cyano-5,7-dimethylimidazo[1,2-a]pyrimidine-2-carboxamide CAS 551921-44-9 chemical structure

Description

As a certified reference material (CRM), (E)-N-((((2-chloro-6-fluorobenzyl)oxy)imino)methyl)-3-cyano-5,7-dimethylimidazo[1,2-a]pyrimidine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

(E)-N-((((2-chloro-6-fluorobenzyl)oxy)imino)methyl)-3-cyano-5,7-dimethylimidazo[1,2-a]pyrimidine-2-carboxamide (CAS 551921-44-9), molecular formula C18H14ClFN6O2 and molecular weight 400.79 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (E)-N-((((2-chloro-6-fluorobenzyl)oxy)imino)methyl)-3-cyano-5,7-dimethylimidazo[1,2-a]pyrimidine-2-carboxamide (C18H14ClFN6O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC18H14ClFN6O2
Molecular Weight400.79 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF/Cl-containing
Nitrogen Atoms6

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