3-[(E)-1-(4-Chlorophenyl)-2-(dimethylamino)ethenesulfonyl]-5-(trifluoromethyl)pyridine-2-carbonitrile CAS 551930-73-5
| CAS No. | 551930-73-5 |
| Molecular Formula | C17H13ClF3N3O2S |
| Molecular Weight | 415.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-[(E)-1-(4-Chlorophenyl)-2-(dimethylamino)ethenesulfonyl]-5-(trifluoromethyl)pyridine-2-carbonitrile.
3-[(E)-1-(4-Chlorophenyl)-2-(dimethylamino)ethenesulfonyl]-5-(trifluoromethyl)pyridine-2-carbonitrile (CAS 551930-73-5), molecular formula C17H13ClF3N3O2S and molecular weight 415.82 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-[(E)-1-(4-Chlorophenyl)-2-(dimethylamino)ethenesulfonyl]-5-(trifluoromethyl)pyridine-2-carbonitrile (C17H13ClF3N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H13ClF3N3O2S |
| Molecular Weight | 415.82 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related E Standards
- 5-((4-Chlorophenyl)sulfonyl)-N-(2,4-difluorophenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 672951-17-6)
- N-(4-Chlorophenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775440-60-2)
- [(3Z)-1-[(4-Chlorophenyl)methyl]-5-nitro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino 3-methylbutanoate (CAS 303998-48-3)
- [(3Z)-1-[(4-Chlorophenyl)methyl]-5-nitro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino pentanoate (CAS 303998-37-0)
- 3-(3-Chlorophenyl)-6,7-diphenyl-2H-oxazolo[3,2-a][1,3,5]triazine-2,4(3H)-dione (CAS 35629-67-5)
- 3-(4-Chlorophenyl)-6,7-diphenyl-2H-oxazolo[3,2-a][1,3,5]triazine-2,4(3H)-dione (CAS 35629-68-6)
- 5-((4-Chlorophenyl)thio)-N-(3-(trifluoromethyl)phenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 303151-35-1)
- 2-[(2-Chlorophenyl)sulfanyl]-3-[3-(trifluoromethyl)phenyl]quinoline (CAS 339103-24-1)
Recommended Standards
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(phenylsulfanyl)pyrrolidine-2,5-dione (CAS 338772-49-9)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(p-tolyl)-1H-pyrrole-2-sulfonamide (CAS 321433-64-1)
- Acemetacin (CAS 53164-05-9)
- N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 882082-22-6)
- 31081-30-8 5-Bromo-2-(4-fluorophenoxy)aniline 9829AD C12H9BrFNO (CAS 31081-30-8)
- 1-(4-((1-Phenyl-1H-tetrazol-5-yl)methyl)piperazin-1-yl)pentan-1-one (CAS 1049423-13-3)
- 2-Benzhydrylaniline (CAS 57259-32-2)
- (S)-N-(Pyrrolidin-3-yl)cyclopropanecarboxamide (CAS 1305350-71-3)
- 7-Methoxy Fenoldopam (CAS 95183-47-4)
- 1-(3-Amino-5-methoxybenzo[b]thiophen-2-yl)ethanone (CAS 1426445-00-2)
- n-(5-Methylisoxazol-3-yl)-2-(pyrrolidin-1-yl)acetamide (CAS 666821-88-1)
- 2-Chloro-n-[1-(3,4-dihydro-2h-1,5-benzodioxepin-7-yl)-2-methylpropyl]acetamide (CAS 848658-75-3)
- 2-Chloro-N-(1-methyl-1,2-dihydro-3H-pyrazol-3-ylidene)acetamide (CAS 957510-87-1)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com