3-Amino-2-thiophenecarboxylic Acid CAS 55341-87-2
| CAS No. | 55341-87-2 |
| Molecular Formula | C5H5NO2S |
| Molecular Weight | 143.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Amino-2-thiophenecarboxylic Acid.
3-Amino-2-thiophenecarboxylic Acid (CAS 55341-87-2) is a high-purity analytical reference standard with the molecular formula C5H5NO2S and a molecular weight of 143.16 g/mol.
3-Amino-2-thiophenecarboxylic Acid (C5H5NO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5NO2S |
| Molecular Weight | 143.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 1-(tert-Butoxycarbonyl)-4-methylpiperidine-3-carboxylic acid (CAS 1009376-52-6)
- (5-(Pyridin-3-yloxy)furan-2-yl)methanol (CAS 857284-15-2)
- 1,1,1,3,3,3-Hexamethyl-2,2-diphenyltrisilane (CAS 18549-83-2)
- 5-Fluoro-2-(methylthio)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 2415255-60-4)
- 2-Methyl-7-nitro-2H-benzo[b][1,4]thiazin-3(4H)-one (CAS 105807-71-4)
- Anorexigenic Peptide (CAS 69275-10-1)
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