4-(2-Fluorophenyl)-N-(2-methoxyphenyl)piperazine-1-carboxamide CAS 553657-41-3
| CAS No. | 553657-41-3 |
| Molecular Formula | C18H20FN3O2 |
| Molecular Weight | 329.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(2-Fluorophenyl)-N-(2-methoxyphenyl)piperazine-1-carboxamide (CAS 553657-41-3) is a high-purity analytical reference standard with the molecular formula C18H20FN3O2 and a molecular weight of 329.37 g/mol.
Based on its molecular formula C18H20FN3O2, 4-(2-Fluorophenyl)-N-(2-methoxyphenyl)piperazine-1-carboxamide contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 329.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-(2-Fluorophenyl)-N-(2-methoxyphenyl)piperazine-1-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20FN3O2 |
| Molecular Weight | 329.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- n-((4-Methyl-4h-1,2,4-triazol-3-yl)methyl)-3-nitropyridin-2-amine (CAS 1178230-73-3)
- 1-Cyclopropyl-N-((4-phenyl-4h-1,2,4-triazol-3-yl)methyl)methanamine (CAS 1311627-18-5)
- (5-((Trimethylsilyl)ethynyl)pyridin-3-yl)boronic acid (CAS 2096339-16-9)
- tert-Butyl 3-nitrobenzoate (CAS 58656-99-8)
- (6E)-6-benzylidene-1-phenyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid (CAS 929974-84-5)
- Methyl 6-cyano-1H-indole-3-carboxylate (CAS 1357147-38-6)
- (1-(2,6-Dichlorobenzyl)piperidin-4-yl)methanol (CAS 1289388-45-9)
- Imidazolidin-4-one hydrochloride (CAS 1373253-20-3)
- β-Asp9-Tirzepatide (CAS CATO-CPTD788931)
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