N-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)-N-(4-fluorophenyl)formamide CAS 553657-57-1

Purity 97%+In StockPharmaceutical Standards
CAS No.553657-57-1
Molecular FormulaC18H19ClFN3O
Molecular Weight347.81 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)-N-(4-fluorophenyl)formamide CAS 553657-57-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 347.81 g/mol gives N-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)-N-(4-fluorophenyl)formamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)-N-(4-fluorophenyl)formamide (CAS 553657-57-1) is a high-purity analytical reference standard with the molecular formula C18H19ClFN3O and a molecular weight of 347.81 g/mol.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)-N-(4-fluorophenyl)formamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 347.81 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)-N-(4-fluorophenyl)formamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H19ClFN3O
Molecular Weight347.81 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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