Cefazolin Impurity 42 CAS 55390-53-9
| CAS No. | 55390-53-9 |
| Molecular Formula | C14H14N8O4S3 |
| Molecular Weight | 454.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Cefazolin Impurity 42 (CAS 55390-53-9, C14H14N8O4S3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C14H14N8O4S3, Cefazolin Impurity 42 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 454.51 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cefazolin Impurity 42 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H14N8O4S3 |
| Molecular Weight | 454.51 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 3 |
Related Cefazolin Standards
- Cefazolin EP Impurity L (CAS CATO-C4X-157710)
- Cefazolin Impurity 41 (CAS CATO-C4X-157741)
- Cefazolin Impurity P5 (CAS CATO-C4X-157749)
- Cefazolin Impurity P4 (CAS 2247245-34-5)
- Cefazolin (CAS 25953-19-9)
- Cefazolin EP Impurity K (Mixture of Diastereomers) (CAS 1322626-65-2)
- Cefazolin Impurity 86 (CAS CATO-C4X-157786)
- Cefazolin EP Impurity K (CAS 2410652-70-7)
Recommended Standards
- (3S,3aS,6R,6aS)-6-{[(4-methylbenzene)sulfonyl]oxy}-hexahydrofuro[3,2-b]furan-3-yl 4-methylbenzene-1-sulfonate 66966-12-9 KS-00002BDF (CAS 66966-12-9)
- Octyl 4-O-(b-D-galactopyranosyl)-β-D-glucopyranoside (CAS 74513-17-0)
- Obacunone (CAS 751-03-1)
- n-Octyl β-D-maltoside (CAS 82494-08-4)
- Phytomenadione/Vitamin K1 Impurity 107 (CAS CATO-C4X-2207107)
- Nicardipine Impurity 26 (CAS 30625-99-1)
- Rilpivirine Impurity 13 (CAS CATO-C4X-136313)
- 1-Bromo-4-butoxy-2-methylbutane (CAS 1494629-02-5)
- 4-(Chlorodifluoromethyl)pyrimidine-5-carbonyl chloride (CAS 185393-14-0)
- 1-(4-(Ethoxycarbonyl)-3,5-dimethyl-1H-pyrrole-2-carbonyl)piperidine-3-carboxylic acid (CAS 1142210-14-7)
- 4-ESTREN-17α-ETHYNYL-17β-OL-3-ONE ACETATE OXIME (CAS 20799-24-0)
- 3-(2-(2-Chloro-4-nitrophenoxy)acetamido)-4-methylbenzene-1-sulfonyl fluoride (CAS 25299-96-1)
- Methyl 1'-tosylspiro[cyclohexane-1,3'-indoline]-5'-carboxylate (CAS 2227206-21-3)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
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