Cefazolin Impurity P4 CAS 2247245-34-5
| CAS No. | 2247245-34-5 |
| Molecular Formula | C14H14N8O4S3 |
| Molecular Weight | 454.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Cefazolin Impurity P4 (C14H14N8O4S3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 454.51 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Cefazolin Impurity P4 (CAS 2247245-34-5, C14H14N8O4S3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H14N8O4S3 |
| Molecular Weight | 454.51 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 3 |
Related Cefazolin Standards
- Cefazolin EP Impurity L (CAS CATO-C4X-157710)
- Cefazolin Impurity 41 (CAS CATO-C4X-157741)
- Cefazolin Impurity 42 (CAS 55390-53-9)
- Cefazolin Impurity P5 (CAS CATO-C4X-157749)
- Cefazolin (CAS 25953-19-9)
- Cefazolin EP Impurity K (Mixture of Diastereomers) (CAS 1322626-65-2)
- Cefazolin Impurity 86 (CAS CATO-C4X-157786)
- Cefazolin EP Impurity K (CAS 2410652-70-7)
Recommended Standards
- Obacunone (CAS 751-03-1)
- Fmoc-leu-bt (CAS 1072840-99-3)
- Methyl (s)-2-((((9h-fluoren-9-yl)methoxy)carbonyl)amino)-4-((tert-butoxycarbonyl)amino)butanoate (CAS 125218-68-0)
- (3S,3aS,6R,6aS)-6-{[(4-methylbenzene)sulfonyl]oxy}-hexahydrofuro[3,2-b]furan-3-yl 4-methylbenzene-1-sulfonate 66966-12-9 KS-00002BDF (CAS 66966-12-9)
- Propranolol Impurity 17 (CAS 4199-10-4)
- Urapidil Impurity 23 (CAS CATO-C4X-192423)
- Travoprost Impurity 20 (CAS 1642863-99-7)
- (2R,3R,4S,5R)-2-(6-(((1S,2S)-2-Hydroxycyclopentyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS 124555-18-6)
- 2-(3-Methoxybenzyl)benzaldehyde (CAS 223575-85-7)
- (S)-5,7-difluorochroman-4-amine (CAS 1212993-64-0)
- N-(3-Bromo-2-(trifluoromethyl)-phenyl)piperidin-1-amine (CAS 1713163-63-3)
- Mivacurium Chloride Impurity 9 (CAS CATO-C4X-13759)
- N-Hydroxy-4-methylbenzimidamide (CAS 19227-13-5)
- Des-Leu26-Tirzepatide (CAS CATO-CPTD788947)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com