o-(2-Fluorobenzyl)hydroxylamine CAS 55418-27-4
| CAS No. | 55418-27-4 |
| Molecular Formula | C7H8FNO |
| Molecular Weight | 141.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including o-(2-Fluorobenzyl)hydroxylamine.
CATO supplies o-(2-Fluorobenzyl)hydroxylamine (CAS 55418-27-4), a certified reference material (molecular formula C7H8FNO, MW 141.14 g/mol) for analytical method development and quality control.
Structurally, o-(2-Fluorobenzyl)hydroxylamine (C7H8FNO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 141.14 g/mol, it falls into the low-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8FNO |
| Molecular Weight | 141.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related o Standards
- O-(4-Fluorobenzyl)hydroxylamine (CAS 1782-40-7)
- 3-Fluorobenzyl chloride (CAS 456-42-8)
- 2-Fluorobenzyl Chloride (CAS 345-35-7)
- 4-Fluorobenzyl Chloride (CAS 352-11-4)
- 4-Fluorobenzyl-α,α-d2 Chloride (CAS 1219804-18-8)
- 3-Fluorobenzyl Cyanide (CAS 501-00-8)
- 4-Fluorobenzyl-2,3,5,6-d4 Chloride (CAS 1219804-10-0)
- 4-Fluorobenzyl-d6 Alcohol (CAS 1071809-48-7)
Recommended Standards
- 6-Fluoro-2-methylpyridine-3-methanol (CAS 884494-98-8)
- (4-amino-2-fluorophenyl)methanol (CAS 840501-15-7)
- 5-Fluoro-2-methoxy-4-picoline (CAS 884495-11-8)
- (R)-1-(5-fluoropyrimidin-2-yl)ethan-1-amine (CAS 1202352-14-4)
- (2-(Methylthio)pyridin-3-yl)(1-oxa-4-thia-8-azaspiro[4.5]decan-8-yl)methanone (CAS 1396558-71-6)
- 1,2,3,6-Tetrachlorodibenzo[b,d]furan (CAS 83704-21-6)
- 4-Benzoyl-1-(2-chlorobenzyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317822-22-3)
- 5-(3-Chloropyridin-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-carboxylic acid (CAS 1423030-58-3)
- 2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-4,5-diphenyl-1-(prop-2-yn-1-yl)-1H-imidazole (CAS 339277-25-7)
- 3,3-Difluorocyclopentanone (CAS 1215071-20-7)
- 4-Carbamoyl-1-methylpyridin-1-ium (CAS 45791-94-4)
- N-Methyl-N-{[3-(trifluoromethyl)phenyl]methyl}piperidin-4-amine (CAS 1155107-33-7)
- 1-(4-Nitrophenyl)cyclopentane-1-carboxylic acid (CAS 52648-77-8)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
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