3-Fluorobenzyl chloride CAS 456-42-8
| CAS No. | 456-42-8 |
| Molecular Formula | C7H6ClF |
| Molecular Weight | 144.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Fluorobenzyl chloride.
3-Fluorobenzyl chloride (CAS 456-42-8), molecular formula C7H6ClF and molecular weight 144.57 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine/chlorine substitution, an aromatic ring system, 3-Fluorobenzyl chloride is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 144.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Fluorobenzyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6ClF |
| Molecular Weight | 144.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Fluorobenzyl Standards
- 2-Fluorobenzyl Chloride (CAS 345-35-7)
- 4-Fluorobenzyl Chloride (CAS 352-11-4)
- 4-Fluorobenzyl-α,α-d2 Chloride (CAS 1219804-18-8)
- O-(4-Fluorobenzyl)hydroxylamine (CAS 1782-40-7)
- o-(2-Fluorobenzyl)hydroxylamine (CAS 55418-27-4)
- 4-Fluorobenzyl-2,3,5,6-d4 Chloride (CAS 1219804-10-0)
- (2-Fluorobenzyl)cyanamide (CAS 1249090-98-9)
- N-(4-Fluorobenzyl)cyanamide (CAS 1255147-62-6)
Recommended Standards
- 4-Chloro-2-fluorotoluene (CAS 452-75-5)
- 5-Chloro-2-fluorotoluene (CAS 452-66-4)
- 4-Chloro-3-fluorotoluene (CAS 5527-94-6)
- 2-Chloro-4-fluorotoluene (CAS 452-73-3)
- [5-Bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-yl]amine (CAS 756503-69-2)
- 1,6-Diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile (CAS 79388-04-8)
- 2-(2,2-Dimethyl-1,3-dioxolan-4-yl)ethyl methanesulfonate (CAS 76099-47-3)
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- Ethyl 6-amino-5-cyano-4-(4-methoxyphenyl)-2-methyl-4H-pyran-3-carboxylate (CAS 89809-76-7)
- 2-(2,3-Difluoro-6-nitrophenyl)acetonitrile (CAS 1803788-44-4)
- 107444-51-9 0JS9125PIZ Glucagon-like peptide 1 (7-36) Glucagon-related peptide 1 (Rana catesbeiana), 3-L-glutamic acid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-30-L-argininamide-31-de-L-proline-32-de-L-lysine- Glp-I (7-36) Proglucagon (78-107) Human glucagon-like peptide-1-(7-36) amide Human GLP-1-(7-36)-amide Glucagon-like peptide-I(7-36) amide Rat GLP-I(7-36)amide Insulinotropin (human) MKC 253 UNII-0JS9125PIZ (CAS 107444-51-9)
Why CATO?
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