3-(2-Chlorophenyl)-6-fluoro-2-methylquinazolin-4(3H)-one CAS 49579-12-6
| CAS No. | 49579-12-6 |
| Molecular Formula | C15H10ClFN2O |
| Molecular Weight | 288.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(2-Chlorophenyl)-6-fluoro-2-methylquinazolin-4(3H)-one.
3-(2-Chlorophenyl)-6-fluoro-2-methylquinazolin-4(3H)-one (CAS 49579-12-6) is a high-purity analytical reference standard with the molecular formula C15H10ClFN2O and a molecular weight of 288.70 g/mol.
The molecular framework of 3-(2-Chlorophenyl)-6-fluoro-2-methylquinazolin-4(3H)-one (C15H10ClFN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(2-Chlorophenyl)-6-fluoro-2-methylquinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10ClFN2O |
| Molecular Weight | 288.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 4-(4-chlorophenyl)-3-(4-fluorophenyl)-1,2-oxazol-5-amine (CAS 1097153-49-5)
- 2-(1-(4-Chlorophenyl)-1H-pyrazol-5-yl)-5-fluorophenol (CAS 876950-42-4)
- 3-(2-Chlorophenyl)-2-(fluoromethyl)quinazolin-4(3H)-one (CAS 61554-54-9)
- 3-(3-Chlorophenyl)-6-fluoro-4-methylcoumarin (CAS 527751-40-2)
- 3-(4-Chlorophenyl)-6-fluoro-4-methylcoumarin (CAS 527751-38-8)
- 1-(3-Chlorophenyl)-5-(furan-2-yl)-1h-pyrazole-3-carboxylic acid (CAS 957013-17-1)
- 1-(4-Chlorophenyl)-5-(furan-2-yl)-1h-pyrazole-3-carboxylic acid (CAS 956769-53-2)
- 4-(4-Chlorophenyl)-1-(6-fluoropyridin-2-yl)-1H-pyrazol-3-amine (CAS 318284-44-5)
Recommended Standards
- 3-(2-Chloro-6-fluorobenzyl)-5-phenyl-1,2,4-oxadiazole (CAS 6180-87-6)
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- 3-Chloro-6-ethoxy-2-fluoro-5-(2-methyl-1,3-dioxolan-2-yl)benzaldehyde (CAS 1995889-49-0)
- 2-Chloro-4-(fluorosulfonyl)phenyl methanesulfonate (CAS 23383-87-1)
- 3-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzenemethanamine (CAS 870562-47-3)
- tert-Butyl (S)-2-(3-(trifluoromethyl)benzyl)piperazine-1-carboxylate (CAS 1260595-99-0)
- (E)-4-(2-Furyl)-3-buten-2-one (CAS 41438-24-8)
- 4-Hydrazinyl-7-methylquinoline (CAS 68500-34-5)
- Methyl thieno[2',3':4,5]imidazo[2,1-b]thiazole-2-carboxylate (CAS 477851-85-7)
- 3-(Benzo[d]thiazol-2-yl)-2,2-difluoropropanoic acid (CAS 1538125-63-1)
- 1-(3-(Aminomethyl)pyrrolidin-1-yl)ethan-1-one dihydrochloride (CAS 1803596-63-5)
- n-(3,4-Dimethoxybenzyl)-5-methyl-3-phenylisoxazole-4-carboxamide (CAS 497061-11-7)
- 4-[(3-Iodophenoxy)methyl]piperidine (CAS 1347292-97-0)
- D-Ser39-Tirzepatide (CAS CATO-CPTD788679)
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