6-Iodo-8-nitroquinoline CAS 5552-46-5
| CAS No. | 5552-46-5 |
| Molecular Formula | C9H5IN2O2 |
| Molecular Weight | 300.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Iodo-8-nitroquinoline.
6-Iodo-8-nitroquinoline (CAS 5552-46-5), molecular formula C9H5IN2O2 and molecular weight 300.05 g/mol, is a CATO reference standard with documented purity and traceability.
6-Iodo-8-nitroquinoline (C9H5IN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Iodo-8-nitroquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5IN2O2 |
| Molecular Weight | 300.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Iodo Standards
- 3-Iodo-6-nitroquinoline (CAS 1802820-05-8)
- 3-Iodo-8-nitroquinoline (CAS 497084-46-5)
- 5-Iodo-6-nitroquinoline (CAS 618397-63-0)
- 5-Iodo-8-nitroisoquinoline (CAS 401916-13-0)
- 5-Iodo-8-nitroquinoline (CAS 859959-56-1)
- 2-Iodo-1,3-dimethyl-5-(trifluoromethyl)benzene (CAS 875550-67-7)
- 4-Iodo-2-(trifluoromethyl)benzaldehyde (CAS 1007579-67-0)
- 2-Iodo-6-(trifluoromethyl)benzaldehyde (CAS 1261612-24-1)
Recommended Standards
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- Perfluorocyclohexane DISCONTINUED (CAS 355-68-0)
- (3-Fluoro-4-methoxy-2-(methylthio)phenyl)methanol (CAS 2090969-41-6)
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- Tert-butyl (S)-8-amino-5-oxa-2-azaspiro[3.4]Octane-2-carboxylate (CAS 2306246-50-2)
- 3-Bromodihydro-2H-thiopyran-4(3H)-one 1,1-dioxide (CAS 162467-21-2)
- (4S,4'S)-2,2'-[2-Phenyl-1-(phenylmethyl)ethylidene]bis[4,5-dihydro-4-(phenylmethyl)oxazole] (CAS 583058-02-0)
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- Ethyl 5-cyano-2-phenyl-6-{[3-(trifluoromethyl)phenyl]sulfanyl}pyridine-3-carboxylate (CAS 306980-03-0)
- Protein Kinase C? Peptide Substrate (CAS 120253-69-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com