Fasudil impurity 67 CAS 55557-00-1
| CAS No. | 55557-00-1 |
| Molecular Formula | C5H10N4O2 |
| Molecular Weight | 158.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Fasudil impurity 67 (CAS 55557-00-1) is a certified pharmaceutical impurity reference standard with the molecular formula C5H10N4O2 and a molecular weight of 158.16 g/mol.
The molecular framework of Fasudil impurity 67 (C5H10N4O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H10N4O2 |
| Molecular Weight | 158.16 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 4 |
Related Fasudil Standards
- Fasudil Impurity 23 (CAS CATO-C4X-136523)
- Fasudil impurity 68 (CAS CATO-C4X-136568)
- Fasudil Impurity 13 (CAS 56344-32-2)
- Fasudil Impurity 58 (CAS 2423988-23-0)
- Fasudil Impurity N2 (CAS 23261-58-7)
- Fasudil Impurity 11 (CAS CATO-C4X-136511)
- Fasudil Impurity 15 (CAS 27655-40-9)
- Fasudil Impurity 16 (CAS 1263357-67-0)
Recommended Standards
- Pomalidomide Impurity 47 (CAS 885278-16-0)
- Doxofylline Impurity 34 (CAS CATO-C4X-151334)
- Gatifloxacin Impurity 20 (CAS 55556-94-0)
- Hydantoin Impurity 20 (CAS CATO-C4X-214620)
- Carboplatin Impurity 10 (CAS 873662-13-6)
- Venetoclax Impurity 8 (CAS 2573767-91-4)
- Methylprednisolone Impurity 54 (CAS CATO-C4X-191954)
- Fosravuconazole Impurity 1 (CAS CATO-C3D-263000)
- [(5-bromofuran-2-yl)methyl](methyl)amine (CAS 889943-39-9)
- (3-(Aminomethyl)piperidin-1-yl)(thiophen-3-yl)methanone (CAS 1250535-86-4)
- 3,3-Bis(5-(tert-butyl)-2-hydroxyphenyl)indolin-2-one (CAS 863779-74-2)
- 3-Amino-1-(4-fluorobenzyl)-4-(p-tolyl)azetidin-2-one (CAS 1291490-60-2)
- 3-(3,4-Dimethylphenoxy)propanoic acid (CAS 25173-39-1)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
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