Pomalidomide Impurity 47 CAS 885278-16-0
| CAS No. | 885278-16-0 |
| Molecular Formula | C9H6N2O |
| Molecular Weight | 158.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Pomalidomide Impurity 47 (CAS 885278-16-0), a pharmacopoeial impurity reference standard (molecular formula C9H6N2O, MW 158.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Pomalidomide Impurity 47 (C9H6N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 158.16 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6N2O |
| Molecular Weight | 158.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Pomalidomide Standards
- Pomalidomide Impurity 3 (CAS 328-48-3)
- Pomalidomide Impurity 12 (CAS 585-21-7)
- Pomalidomide Impurity 13 (CAS 636-65-7)
- Pomalidomide Impurity 7 (CAS 5434-21-9)
- Pomalidomide Impurity 9 (CAS 498-25-9)
- Pomalidomide Impurity 46 (CAS 944709-53-9)
- Pomalidomide Impurity 36 (CAS 641-70-3)
- Pomalidomide Impurity 37 (CAS 5466-84-2)
Recommended Standards
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- Abacavir EP Impurity A (CAS 136470-79-6)
- Trazodone impurity 68 (CAS 2221987-86-4)
- Arotinolol Impurity 14 (CAS 1701418-50-9)
- 1-{2-amino-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-6-yl}ethan-1-one (CAS 1100752-63-3)
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- Microcystin-YR (CAS 101064-48-6)
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