Loxoprofen impurity 85 CAS 335096-46-3
| CAS No. | 335096-46-3 |
| Molecular Formula | C13H18O8 |
| Molecular Weight | 302.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Loxoprofen impurity 85 (CAS 335096-46-3), a pharmacopoeial impurity reference standard (molecular formula C13H18O8, MW 302.28 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Loxoprofen impurity 85 (C13H18O8) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18O8 |
| Molecular Weight | 302.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
Related Loxoprofen Standards
- Loxoprofen Impurity 66 (CAS 334948-52-6)
- Loxoprofen Impurity 132 (CAS CATO-C4X-1488132)
- Loxoprofen Impurity 70 (CAS 1027957-36-3)
- Loxoprofen Impurity 7 (CAS CATO-C4X-14887)
- Loxoprofen Impurity 77 (CAS CATO-C4X-148877)
- Loxoprofen Impurity 78 (CAS CATO-C4X-148878)
- Loxoprofen impurity 124 (CAS CATO-C4X-1488124)
- Loxoprofen Impurity 161 (CAS CATO-C4X-1488161)
Recommended Standards
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Why CATO?
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