Neomycin Impurity N1 CAS 55781-25-4
| CAS No. | 55781-25-4 |
| Molecular Formula | C17H33N3O11 |
| Molecular Weight | 455.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Neomycin Impurity N1 is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Neomycin Impurity N1 (CAS 55781-25-4, C17H33N3O11) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Neomycin Impurity N1 (C17H33N3O11) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Neomycin Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H33N3O11 |
| Molecular Weight | 455.46 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 3 |
Related Neomycin Standards
- Neomycin Impurity 13 (CAS 58152-23-1)
- Neomycin EP Impurity B (CAS 54617-39-9)
- Neomycin Impurity 18 (CAS CATO-C4X-184518)
- Neomycin Impurity 17 (CAS CATO-C4X-184517)
- Neomycin Sulfate EP Impurity A (CAS 3947-65-7)
- Neomycin Impurity 14 (CAS CATO-C4X-184514)
- Neomycin (CAS 1404-04-2)
- Neomycin EP Impurity C (CAS 66-86-4)
Recommended Standards
- N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide (CAS 31505-87-0)
- Minocycline EP Impurity H (CAS 1346598-44-4)
- N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-(((S)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide (CAS 97672-60-1)
- Minocycline Impurity 51 (CAS CATO-C4X-169951)
- Bempedoic Acid Impurity 17 (CAS 2570179-40-5)
- Dotinurad Impurity 114 (CAS CATO-C4X-2494114)
- Isavuconazole Impurity 99 Iodization HCl (CAS CATO-C4X-123699)
- Quinolinium, 1-ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]-, bromide (CAS 1613-31-6)
- Methyl 4-fluoro-5-iodo-2-methoxybenzoate (CAS 1171824-17-1)
- Caulophyllogenin (CAS 52936-64-8)
- (S)-2-Hydroxy-2’-[(R)-hydroxy(4-pyridyl)methyl]-[1,1’-binaphthalene] (CAS 1498319-66-6)
- Methyl 3-bromo-2-chloropyridine-4-carboxylate (CAS 1214385-62-2)
- 2-Cyclohexylamino-5-methyl-3-nitropyridine (CAS 1033202-68-4)
- Dendroaspis Natriuretic Peptide (CAS 255721-52-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com