Neomycin Sulfate EP Impurity A CAS 3947-65-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.3947-65-7
Molecular FormulaC12H26N4O6
Molecular Weight322.36 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Neomycin Sulfate EP Impurity A CAS 3947-65-7 chemical structure

Description

CATO manufactures Neomycin Sulfate EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

As a process- or degradation-related impurity, Neomycin Sulfate EP Impurity A (CAS 3947-65-7, C12H26N4O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Neomycin Sulfate EP Impurity A is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 322.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC12H26N4O6
Molecular Weight322.36 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1958
Nitrogen Atoms4

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