5-Phenyl-1,3,4-thiadiazole-2-thiol CAS 5585-19-3
| CAS No. | 5585-19-3 |
| Molecular Formula | C8H6N2S2 |
| Molecular Weight | 194.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Phenyl-1,3,4-thiadiazole-2-thiol (CAS 5585-19-3) is a high-purity analytical reference standard with the molecular formula C8H6N2S2 and a molecular weight of 194.28 g/mol.
The molecular framework of 5-Phenyl-1,3,4-thiadiazole-2-thiol (C8H6N2S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Phenyl-1,3,4-thiadiazole-2-thiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6N2S2 |
| Molecular Weight | 194.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Phenyl Standards
- 3-Phenyl-1,2,4-thiadiazole-5-thiol (CAS 20069-34-5)
- 4-Phenyl-1,2,3-thiadiazole-5-thiol (CAS 215296-45-0)
- 1,3,4-Thiadiazole-2-methanol, 5-bromo-(5-bromo-1,3,4-thiadiazol-2-yl)methanol (CAS 1339055-00-3)
- 5-Ethyl-1,3,4-thiadiazole-2-sulfonamide (CAS 66464-91-3)
- 4-Propyl-1,2,3-thiadiazole-5-carbonyl chloride (CAS 1397293-97-8)
- 5-Phenyl-1,3,4-thiadiazole-2-carbaldehyde (CAS 99066-69-0)
- 5-Methyl-1,3,4-thiadiazole-2-sulfonyl chloride (CAS 184222-90-0)
- 4-(1,2,3-Thiadiazole-4-carbonyl)morpholine (CAS 478261-73-3)
Recommended Standards
- 7-amino-6-methyl-1,8-naphthyridine-3-carbonitrile (CAS 2691878-58-5)
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- Cinnoline-4,6-dithiol (CAS 6959-57-5)
- 4-(4-Pyridyl)thiazole-2(3H)-thione (CAS 77168-63-9)
- tert-Butyl 4-(6-chloro-8-fluoroquinazolin-4-yl)piperazine-1-carboxylate (CAS 2101287-23-2)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropane-1-carboxamide (CAS 854267-93-9)
- 1,1-Cyclopropanedicarboxylic acid dimethyl ester (CAS 6914-71-2)
- Naphtho[1,2-c:5,6-c’]difuran-1,3,6,8-tetraone (CAS 3711-03-3)
- 2-Methoxy-N-((tetrahydro-2H-pyran-4-yl)methyl)ethan-1-amine (CAS 1247197-13-2)
- 6-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)nicotinaldehyde (CAS 157169-61-4)
- 2-bromo-N-(2,3-dihydro-1H-inden-5-yl)-3-methylbutanamide (CAS 1016519-25-7)
- Benzyl (5-aminopentyl)carbamate (CAS 69747-36-0)
- Methyl 4-((3-methyl-1-phenyl-1H-pyrazol-5-yl)carbamoyl)benzoate (CAS 1172876-74-2)
- Tirzepatide Impurity 61 (CAS CATO-C4X-324061)
Why CATO?
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