Tizanidine EP Impurity D CAS 560120-68-5
| CAS No. | 560120-68-5 |
| Molecular Formula | C8H7ClN4S2 |
| Molecular Weight | 258.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tizanidine EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Tizanidine EP Impurity D (CAS 560120-68-5), a pharmacopoeial impurity reference standard (molecular formula C8H7ClN4S2, MW 258.75 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tizanidine EP Impurity D (C8H7ClN4S2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 258.75 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN4S2 |
| Molecular Weight | 258.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Tizanidine Standards
- Tizanidine-D4 (CAS 1188331-19-2)
- Tizanidine Impurity 51 (CAS CATO-C4X-144551)
- Tizanidine impurity 22 (CAS CATO-C4X-144522)
- Tizanidine (CAS 51322-75-9)
- Tizanidine impurity 25 (CAS CATO-C4X-144525)
- Tizanidine impurity 31 (CAS CATO-C4X-144531)
- Tizanidine Impurity 41 (CAS CATO-C4X-144541)
- Tizanidine Impurity 42 (CAS CATO-C4X-144542)
Recommended Standards
- U0MP1K4TL8 69812-29-9 EINECS 274-127-7 2-Acetamido-4-methylthiazole-5-sulphonyl chloride 5-Thiazolesulfonyl chloride, 2-(acetylamino)-4-methyl- UNII-U0MP1K4TL8 2-Acetamido-4-methylthiazole-5-sulfonyl chloride (CAS 69812-29-9)
- 6-((2-Chlorophenyl)thio)hexanoic acid (CAS 1004781-64-9)
- 7-Benzyl-4-chloro-5,6,7,8-tetrahydro-1,7-naphthyridine (CAS 911010-92-9)
- 2-(4-tert-Butylphenyl)ethene-1-sulfonyl chloride (CAS 1161945-03-4)
- Lysine Impurity 1 DiHCl (CAS 52123-30-5)
- Rocuronium Impurity 31 (CAS 212505-49-2)
- Aprepitant impurity 33 (CAS 599162-15-9)
- (R)-6,7-Dihydro-5H-cyclopenta[b]pyridin-7-ol (CAS 912277-45-3)
- 3-[(2-Aminoethyl)sulfanyl]-1-ethylpyrrolidine-2,5-dione (CAS 1157103-44-0)
- 2-(7-Hydroxy-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)acetic acid (CAS 459427-55-5)
- 1-(2,2,2-Trifluoroethyl)-1H-imidazole-4-sulfonyl chloride (CAS 1342246-36-9)
- N-Methyl-1h-imidazole-4-ethanamine (CAS 673-50-7)
- n-[(2,4-difluorophenyl)methyl]prop-2-enamide (CAS 1248308-60-2)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
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