2-Bromo-2’,6’-difluoroacetophenone CAS 56159-89-8
| CAS No. | 56159-89-8 |
| Molecular Formula | C8H5BrF2O |
| Molecular Weight | 235.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Bromo-2’,6’-difluoroacetophenone (CAS 56159-89-8), molecular formula C8H5BrF2O and molecular weight 235.03 g/mol, is a CATO reference standard with documented purity and traceability.
2-Bromo-2’,6’-difluoroacetophenone (C8H5BrF2O) contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5BrF2O |
| Molecular Weight | 235.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4'-Bromo-2',3'-difluoroacetophenone (CAS 1007346-28-2)
- 3’-Bromo-2’,4’-difluoroacetophenone (CAS 1210824-63-7)
- 4-Bromo-2,5-difluoroacetophenone, 97% (CAS 123942-11-0)
- 1-(2-Bromo-4,5-difluorophenyl)ethanone (CAS 127371-55-5)
- 5-Bromo-2,4-difluoro-3-methylbenzaldehyde (CAS 1378865-38-3)
- 5-Bromo-2-(2,2-difluorocyclopropyl)pyrimidine (CAS 1393572-03-6)
- 1-(4-Bromo-3,5-difluorophenyl)ethanone (CAS 1528607-78-4)
- 1-(6-Bromo-2,3-difluorophenyl)ethanone (CAS 1542563-93-8)
Recommended Standards
- 2-Bromo-2',3'-difluoroacetophenone (CAS 886762-77-2)
- 2-Bromo-5,6-difluoro-3-methylbenzaldehyde (CAS 2241721-63-9)
- 2-Bromo-1-(3,5-difluorophenyl)ethanone (CAS 220607-75-0)
- 2-Hydrazinyl-3-iodopyridine (CAS 54231-42-4)
- 6-(3-Fluoro-2-methylphenyl)nicotinic acid (CAS 1261889-85-3)
- (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(3,4-dihydroxyphenyl)propanoate (CAS 37169-36-1)
- tert-Butyl 2-oxo-1,3,4,4a,5,7,8,8a-octahydro-1,6-naphthyridine-6-carboxylate (CAS 1221818-65-0)
- 4-Fluoro-N-(4-fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide (CAS 868371-11-3)
- 3,3'-Bis(3,5-dichlorophenyl)-[1,1'-binaphthalene]-2,2'-diol (CAS 1706459-29-1)
- 4-(Difluoromethoxy)-2-(trifluoromethoxy)phenol (CAS 1261760-95-5)
- tert-Butyl (5-aminopyrazin-2-yl)carbamate (CAS 920313-67-3)
- N-Benzyl-1-(4-ethoxyphenyl)methanamine 333755-96-7 (CAS 333755-96-7)
- 1-(2-methoxyethyl)-1H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine (CAS 1481032-08-9)
- Des-Leu26-Tirzepatide (CAS CATO-CPTD788947)
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