Fluoxetine Impurity 51 CAS 56161-72-9
| CAS No. | 56161-72-9 |
| Molecular Formula | C17H18F3NO |
| Molecular Weight | 309.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Fluoxetine Impurity 51 (CAS 56161-72-9), a pharmacopoeial impurity reference standard (molecular formula C17H18F3NO, MW 309.33 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Fluoxetine Impurity 51 (C17H18F3NO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 309.33 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H18F3NO |
| Molecular Weight | 309.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoxetine Standards
- Fluoxetine Impurity 11 (CAS 56161-71-8)
- Fluoxetine Impurity 12 (CAS CATO-C4X-135212)
- Fluoxetine (CAS 54910-89-3)
- Fluoxetine Impurity 20 (CAS CATO-C4X-135220)
- Fluoxetine-D5 (CAS 1173147-79-9)
- Fluoxetine Impurity 24 (CAS CATO-C4X-135224)
- Fluoxetine Impurity 26 (CAS 103756-12-3)
- Fluoxetine Impurity 31 (CAS 5409-66-5)
Recommended Standards
- 3-hydroxy-2-[(2-naphthylsulfonyl)amino]butanoic acid (CAS 1008972-08-4)
- 946682-74-2 T5861 [2-(2-isopropyl-5-methylphenoxy)-5-(trifluoromethyl)phenyl]amine sulfate (salt) (CAS 946682-74-2)
- Methyl 5-(N-(4-ethylphenyl)sulfamoyl)-1H-pyrazole-4-carboxylate (CAS 1037289-09-0)
- N-(2,5-difluorophenyl)-2-((4,6-dimethylpyrimidin-2-yl)thio)acetamide (CAS 303091-58-9)
- Tedizolid Impurity 23 (CAS CATO-C4X-105423)
- Vancomycin EP Impurity G (CAS CATO-C4X-17758)
- Rimegepant Impurity 140 (CAS CATO-C4X-2487140)
- (4-Methylphenyl) N-pyridin-2-ylcarbamate (CAS 469891-28-9)
- (1E)-N-(Isoquinolin-5-yl)-1-[4-(trifluoromethoxy)phenyl]methanimine (CAS 866150-38-1)
- 2-methyl-7-azaspiro[3.5]nonan-2-ol hydrochloride (CAS 1630907-15-1)
- Ethyl hex-5-ynoate (CAS 108545-38-6)
- 4-((4-Chlorobenzyl)oxy)-3-methyl-3H-imidazo[4,5-c]pyridine (CAS 87034-95-5)
- 5-{[2-(tert-butoxy)-2-oxoethoxy]methyl}-1,3-oxazole-4-carboxylic acid (CAS 1909319-49-8)
- C-Peptide (human) (CAS 33017-11-7)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com