Vancomycin EP Impurity G CAS CATO-C4X-17758
| CAS No. | CATO-C4X-17758 |
| Molecular Formula | C66H72Cl2N8O24 |
| Molecular Weight | 1432.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Vancomycin EP Impurity G (CAS CATO-C4X-17758, C66H72Cl2N8O24) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C66H72Cl2N8O24, Vancomycin EP Impurity G contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 1432.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C66H72Cl2N8O24 |
| Molecular Weight | 1432.22 g/mol |
| Purity | >90%>90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 34.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Vancomycin Standards
- Vancomycin impurity 24 (CAS CATO-C4X-177524)
- Vancomycin EP Impurity A (CAS 91700-98-0(Free Base))
- Vancomycin impurity 23 (CAS CATO-C4X-177523)
- Vancomycin impurity 25 (CAS CATO-C4X-177525)
- Vancomycin EP Impurity I (CAS CATO-C4X-177510)
- Vancomycin EP Impurity J (CAS 2416251-24-4)
- Vancomycin Impurity M (CAS CATO-C4X-177522)
- Vancomycin impurity 26 (CAS CATO-C4X-177526)
Recommended Standards
- D-Arg8-Cetrorelix (CAS CATO-C4X-201427)
- Sulfitocobalamin Sodium Salt (CAS CATO-C4X-18742)
- 【肽序重复停用见C4X-201413】Cetrorelix Impurity 24 (CAS CATO-C4X-201424)
- Deamidated Cetrorelix (CAS CATO-C4X-201413)
- Oseltamivir Impurity 24 (CAS 1132659-96-1)
- Ertapenem Impurity 1 (Ring Open) (CAS CATO-C4X-16331)
- Peficitinib Impurity 12 (CAS 944118-02-9)
- 1-Ethyl-3-methyl-N-((1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)methyl)-1H-pyrazol-5-amine hydrochloride (CAS 1856100-66-7)
- Ethyl(4-fluoro-2-methoxyphenyl)sulfane (CAS 1314937-91-1)
- N-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]pent-4-ynamide (CAS 2408797-66-8)
- 4-(2,4,6-Trimethylbenzyl)piperidin-4-ol (CAS 1225735-51-2)
- D-GLUCOSE 13C (CAS 101615-88-7)
- tert-Butyl (2-chloro-6-methylpyridin-4-yl)carbamate (CAS 1266335-92-5)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
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