5,6-Dihydrouridine CAS 5627-05-4
| CAS No. | 5627-05-4 |
| Molecular Formula | C9H14N2O6 |
| Molecular Weight | 246.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5,6-Dihydrouridine.
5,6-Dihydrouridine (CAS 5627-05-4) is a high-purity analytical reference standard with the molecular formula C9H14N2O6 and a molecular weight of 246.22 g/mol.
5,6-Dihydrouridine (C9H14N2O6) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H14N2O6 |
| Molecular Weight | 246.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Recommended Standards
- 5,6-Dihydro-ara-uridine (CAS 30100-83-5)
- 5,6-Dihydroxy-2-(p-tolyl)pyrimidine-4-carboxylic acid (CAS 954241-09-9)
- 5-(Benzo[d][1,3]dioxol-5-yl)-2-methylfuran-3-carboxylic acid (CAS 696627-46-0)
- 5-[(2-Formylphenoxy)methyl]-2-furoic acid (CAS 881041-12-9)
- ditert-butyl 6-formyl-7-methyl-spiro[3,4-dihydro-1,8-naphthyridine-2,3'-pyrrolidine]-1,1'-dicarboxylate (CAS 2755893-32-2)
- 1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-amine (CAS 1928748-31-5)
- (R)-Methyl 4-((7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxybenzoate (CAS 1333493-12-1)
- 3-(2-Methoxybenzyl)-5,6-dihydro-4H-pyrrolo[3,2-d]isoxazole (CAS 603067-66-9)
- tert-Butyl 7-cyano-3,4-dihydro-2,6-naphthyridine-2(1H)-carboxylate (CAS 2750527-52-5)
- CAS 1406-18-4 (CAS 1406-18-4)
- Entacapone Impurity 59 (CAS CATO-C4X-162959)
- 2-Amino-2-(3-bromophenyl)propan-1-ol (CAS 1183013-69-5)
- Anthracene (CAS 120-12-7)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
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