Entacapone Impurity 59 CAS CATO-C4X-162959
| CAS No. | CATO-C4X-162959 |
| Molecular Formula | C10H6N2O6 |
| Molecular Weight | 250.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Entacapone Impurity 59 (CAS CATO-C4X-162959, C10H6N2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Entacapone Impurity 59 (C10H6N2O6) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Entacapone Impurity 59 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6N2O6 |
| Molecular Weight | 250.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Entacapone Standards
- Entacapone EP Impurity F (CAS 160391-70-8)
- Entacapone impurity 42 (CAS CATO-C4X-162942)
- Entacapone Impurity 6 (CAS 158693-01-7)
- Entacapone Impurity 1 (CAS CATO-C4X-16291)
- Entacapone EP Impurity G (CAS 1364322-41-7)
- Entacapone impurity 18 (CAS CATO-C4X-162918)
- Entacapone impurity 53 (CAS CATO-C4X-162953)
- Entacapone impurity 52 (CAS CATO-C4X-162952)
Recommended Standards
- Pyridoxal 5'-Phosphate-d3 (CAS 1354560-58-9)
- 948291-36-9 2,5-Dichloro-8-methylquinoline-3-carboxaldehyde MFCD09787537 (CAS 948291-36-9)
- Malic Acid Impurity 10 (CAS 1800467-68-8)
- 938138-94-4 2,6-Dichloro-8-methylquinoline-3-carboxaldehyde MFCD09702833 (CAS 938138-94-4)
- Remdesivir Impurity 24 (CAS CATO-C4X-210024)
- Orforglipron Impurity 14 (CAS CATO-C4X-323414)
- Nicorandil Impurity N18 (CAS 54120-68-2)
- Epinephrine /Adrenaline Impurity 105 (CAS CATO-C4X-1849105)
- Sapecin (CAS 119938-54-4)
- Deferoxamine Mesylate (300 mg) (CAS 138-14-7)
- 479482-38-7 6-Chloro-4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1,2-dihydro-1lambda~6~-thieno[2,3-e][1,2]thiazine-3-carboxamide DTXSID50715839 (CAS 479482-38-7)
- 5-Methyl-6-nitroindazole (CAS 72521-00-7)
- 3,6-Dimethylimidazo[1,5-a]pyridine (CAS 1823373-45-0)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
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