Cefuroxime Sodium EP Impurity A CAS 56271-94-4
| CAS No. | 56271-94-4 |
| Molecular Formula | C15H15N3O7S |
| Molecular Weight | 381.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Cefuroxime Sodium EP Impurity A (CAS 56271-94-4), a pharmacopoeial impurity reference standard (molecular formula C15H15N3O7S, MW 381.36 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C15H15N3O7S, Cefuroxime Sodium EP Impurity A contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 381.36 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H15N3O7S |
| Molecular Weight | 381.36 g/mol |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cefuroxime Standards
- Cefuroxime impurity 107 (CAS CATO-C4X-1245107)
- Cefuroxime Impurity 25 (CAS CATO-C4X-124525)
- Cefuroxime Open-ring Impurity 44 (CAS 1177709-12-4)
- Cefuroxime Impurity 50 (CAS CATO-C4X-124550)
- Cefuroxime Impurity 51 (CAS 213912-35-7)
- Cefuroxime Sodium EP Impurity F (CAS 97170-19-9)
- Cefuroxime Impurity 80 (CAS CATO-C4X-124580)
- Cefuroxime Impurity 86 (CAS CATO-C4X-124586)
Recommended Standards
- 2-(((1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)ethane-1-sulfonic acid (CAS 497258-53-4)
- 2-((2,6-Dichlorobenzyl)thio)-1-(prop-2-yn-1-yl)-4,5-dipropyl-1H-imidazole (CAS 338966-13-5)
- (E)-{1-[2-(4-fluorophenyl)cyclopropyl]ethylidene}({2-[3-(trifluoromethyl)phenoxy]ethoxy})amine (CAS 338401-23-3)
- Tribenuron (CAS 106040-48-6)
- Cholecalciferol EP Impurity C (CAS 5226-01-7)
- Ampicillin Impurity 86 (CAS CATO-C4X-144386)
- Ipragliflozin Impurity 5 (CAS CATO-C4X-18855)
- Ketoprofen D-Lysinate (CAS 1544601-57-1)
- (Z)-2-cyano-3-hydroxy-N-(3-(trifluoromethyl)phenyl)but-2-enamide (CAS 63927-52-6)
- 2-(2-Chloro-4,6-dimethylphenoxy)acetamide (CAS 1030553-87-7)
- 2-Isopropyl-1-methoxy-4-methylbenzene (CAS 31574-44-4)
- (1R,6R)-7-Cbz-3,7-diazabicyclo[4.2.0]octane (CAS 1932046-84-8)
- 6-chloro-4-hydroxy-8-methoxyquinoline-3-carboxylic acid (CAS 1189106-26-0)
- Glucagon-like peptide 2 (CAS 89750-15-2)
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