Cefuroxime Impurity 51 CAS 213912-35-7
| CAS No. | 213912-35-7 |
| Molecular Formula | C15H15N3O7S |
| Molecular Weight | 381.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Cefuroxime Impurity 51 (CAS 213912-35-7) is a certified pharmaceutical impurity reference standard with the molecular formula C15H15N3O7S and a molecular weight of 381.36 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Cefuroxime Impurity 51 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 381.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H15N3O7S |
| Molecular Weight | 381.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2018 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cefuroxime Standards
- Cefuroxime Sodium EP Impurity A (CAS 56271-94-4)
- Cefuroxime impurity 107 (CAS CATO-C4X-1245107)
- Cefuroxime Impurity 25 (CAS CATO-C4X-124525)
- Cefuroxime Open-ring Impurity 44 (CAS 1177709-12-4)
- Cefuroxime Impurity 50 (CAS CATO-C4X-124550)
- Cefuroxime Sodium EP Impurity F (CAS 97170-19-9)
- Cefuroxime Impurity 80 (CAS CATO-C4X-124580)
- Cefuroxime Impurity 86 (CAS CATO-C4X-124586)
Recommended Standards
- Metsulfuron-Methyl (CAS 74223-64-6)
- 6-(3-Fluorophenyl)-N-[1-(2,2,2-trifluoroethyl)-4-piperidyl]nicotinamide (CAS 1033836-12-2)
- 2-(((1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)ethane-1-sulfonic acid (CAS 497258-53-4)
- Levofloxacin Impurity N27 (CAS 1036016-10-0)
- Fudosteine Impurity 8 (CAS CATO-C4X-14478)
- Clindamycin Impurity 59 (CAS CATO-C4X-134159)
- Efinaconazole Impurity 26 (CAS 2055038-63-4)
- N-Benzylnaphthalen-2-amine (CAS 13672-18-9)
- Cyclopentyl(3-methylpyridin-2-yl)methanamine (CAS 1250429-50-5)
- 3-((1-Isopropyl-1H-pyrazol-4-yl)oxy)propanoic acid (CAS 1603039-75-3)
- 6-Nitrochroman-3-one (CAS 178262-27-6)
- HPA-12 (CAS 383418-30-2)
- 4-Amino-N-(furan-2-yl)benzamide (CAS 436088-30-1)
- Delicious Peptide (bovine) (CAS 73984-05-1)
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