2-(Methoxymethyl)phenol CAS 5635-98-3
| CAS No. | 5635-98-3 |
| Molecular Formula | C8H10O2 |
| Molecular Weight | 138.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(Methoxymethyl)phenol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(Methoxymethyl)phenol (CAS 5635-98-3), molecular formula C8H10O2 and molecular weight 138.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(Methoxymethyl)phenol (C8H10O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Methoxymethyl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10O2 |
| Molecular Weight | 138.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Methoxymethyl Standards
- 3-(Methoxymethyl)phenol (CAS 57234-51-2)
- 4-(Methoxymethyl)phenol (CAS 5355-17-9)
- 4-(Methoxymethyl)pyridin-2-amine (CAS 1125398-71-1)
- 3-(Methoxymethyl)pyridin-2-amine (CAS 1248511-27-4)
- 2-(Methoxymethyl)pyridin-4-amine (CAS 1538416-23-7)
- 6-(Methoxymethyl)pyridin-2-amine (CAS 153959-27-4)
- 1-(Methoxymethyl)-5-vinyl-1H-imidazole (CAS 160425-47-8)
- 2-(Methoxymethyl)-4-methylpyrimidine (CAS 89966-95-0)
Recommended Standards
- 2-(Hydroxymethyl)-6-methylphenol (CAS 22470-99-1)
- 2,6-Dimethylhydroquinone (CAS 654-42-2)
- 2-(Hydroxymethyl)-5-methylphenol (CAS 7405-12-1)
- 2-Allyl-4-hydroxycyclopent-2-en-1-one (CAS 61369-21-9)
- 4-Benzyl 1-(tert-butyl) 2,6-dimethylpiperazine-1,4-dicarboxylate (CAS 1207455-37-5)
- 3,4-Dibromo-5-fluorobenzylamine (CAS 1803777-87-8)
- 2-((N-benzyl-4-methylphenyl)sulfonamido)-N-(5-chloro-2-methoxyphenyl)acetamide (CAS 332163-70-9)
- 3-Cyclobutyl-7-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine (CAS 1389321-47-4)
- 4-(3-Nitrophenyl)-2-(trifluoromethyl)thiazole (CAS 1432053-91-2)
- (R,R,R)-Triglycidyl Isocyanurate (CAS 240408-78-0)
- Chlorhexidine EP Impurity O 2HCl (CAS 2508008-02-2 (free base))
- 4-Chloro-1-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carbonitrile (CAS 338395-88-3)
- 3-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)propanenitrile (CAS 1268336-32-8)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
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