Tulobuterol Impurity 22 CAS 5639-00-9
| CAS No. | 5639-00-9 |
| Molecular Formula | C12H17Cl2NO |
| Molecular Weight | 262.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tulobuterol Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Tulobuterol Impurity 22 (CAS 5639-00-9, C12H17Cl2NO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Tulobuterol Impurity 22 (C12H17Cl2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H17Cl2NO |
| Molecular Weight | 262.18 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tulobuterol Standards
- Tulobuterol Impurity 15 (CAS CATO-C4X-213415)
- Tulobuterol Impurity 26 (CAS CATO-C4X-213426)
- Tulobuterol Impurity 25 (CAS CATO-C4X-213425)
- Tulobuterol Impurity 27 (CAS CATO-C4X-213427)
- Tulobuterol Impurity 13 (CAS CATO-C4X-213413)
- Tulobuterol Impurity 35 (CAS 1597775-10-4)
- Tulobuterol Impurity 18 (CAS CATO-C4X-213418)
- Tulobuterol Impurity 23 (CAS CATO-C4X-213423)
Recommended Standards
- Sitagliptin impurity 145 (CAS CATO-C4X-1144145)
- Bis(4-hydroxyphenyl) Sulfone -13C12 (CAS 1991267-29-8)
- N-[2-(2,4-Dichlorophenoxy)ethyl]-2-methyl-2-propanamine (CAS 356532-97-3)
- 2-Bromo-3-methyl-1-(3-methylpiperidin-1-yl)butan-1-one (CAS 1016737-57-7)
- Sevoflurane Impurity 8 (CAS 79507-76-9)
- Bisoprolol Impurity 57 Fumarate (CAS CATO-C4X-124757)
- Avibactam Impurity 124 (CAS CATO-C4X-1348124)
- 2-(Chloromethyl)-4-(trifluoromethoxy)benzo[d]oxazole (CAS 1806517-07-6)
- (trans-3-Fluoro-1-(3-fluoropyridin-2-yl)cyclobutyl)methanamine (CAS 1344145-39-6)
- (R)-2-((tert-Butoxycarbonyl)amino)-2-(1-methylcyclohexyl)acetic acid (CAS 1200405-64-6)
- N-Ethyl-2-(2-methoxyphenoxy)ethanamine (CAS 4766-09-0)
- Montelukast Impurity 40 (CAS CATO-C4X-103140)
- 1-(2-Methoxyethyl)-3-(4-(5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl)urea (CAS 1206998-56-2)
- Palmitoyl Tripeptide-8 TFA salt (CAS 936544-53-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com