Sitagliptin impurity 145 CAS CATO-C4X-1144145
| CAS No. | CATO-C4X-1144145 |
| Molecular Formula | C12H17Cl2NO |
| Molecular Weight | 262.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Sitagliptin impurity 145 (CAS CATO-C4X-1144145), a pharmacopoeial impurity reference standard (molecular formula C12H17Cl2NO, MW 262.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C12H17Cl2NO, Sitagliptin impurity 145 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 262.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Sitagliptin impurity 145 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17Cl2NO |
| Molecular Weight | 262.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Sitagliptin Standards
- Sitagliptin Impurity 14 (CAS 1151240-91-3)
- Sitagliptin Impurity 966 (CAS 1151240-88-8)
- Sitagliptin Impurity 51 (CAS 1485732-85-1)
- Sitagliptin Impurity 157 (CAS 2110445-12-8)
- Sitagliptin Impurity 164 (CAS 1496395-30-2)
- Sitagliptin Impurity 168 (CAS CATO-C4X-1144168)
- Sitagliptin Impurity 171 (CAS CATO-C4X-1144171)
- Sitagliptin Impurity 172 (CAS CATO-C4X-1144172)
Recommended Standards
- N-[2-(2,4-Dichlorophenoxy)ethyl]-2-methyl-2-propanamine (CAS 356532-97-3)
- Tulobuterol Impurity 22 (CAS 5639-00-9)
- n-(2-(3,4-Dichlorophenoxy)ethyl)butan-2-amine (CAS 851628-47-2)
- Bis(4-hydroxyphenyl) Sulfone -13C12 (CAS 1991267-29-8)
- Propranolol Impurity 52 (CAS CATO-C4X-151952)
- Osimertinib Impurity 53 (CAS CATO-C4X-204553)
- LCZ-696 Impurity 55 (CAS 1573000-33-5)
- Fosinopril Related Compound D (CAS 1356353-41-7)
- 4,4''-Dibromo-4',5'-bis(4-bromophenyl)-1,1':2',1''-terphenyl (CAS 1347702-48-0)
- (4-Amino-2-fluorophenyl)boronic acid (CAS 921211-27-0)
- 2-Bromo-7-methylbenzo[d]thiazole, 97% (CAS 3622-44-4)
- 11-(Triethoxysilyl)undecan-1-amine (CAS 116821-45-5)
- Ethyl 8-(4-bromophenyl)-8-oxooctanoate (CAS 362669-43-0)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com