2-{[3-(difluoromethoxy)phenyl]formamido}acetic acid CAS 565167-97-7
| CAS No. | 565167-97-7 |
| Molecular Formula | C10H9F2NO4 |
| Molecular Weight | 245.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-{[3-(difluoromethoxy)phenyl]formamido}acetic acid.
2-{[3-(difluoromethoxy)phenyl]formamido}acetic acid (CAS 565167-97-7) is a high-purity analytical reference standard with the molecular formula C10H9F2NO4 and a molecular weight of 245.18 g/mol.
Based on its molecular formula C10H9F2NO4, 2-{[3-(difluoromethoxy)phenyl]formamido}acetic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 245.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-{[3-(difluoromethoxy)phenyl]formamido}acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9F2NO4 |
| Molecular Weight | 245.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related difluoromethoxy Standards
- 3-(4-(Difluoromethoxy)-3-nitrophenyl)propanal (CAS 1806647-91-5)
- 2-{[2-(difluoromethoxy)phenyl]formamido}acetic acid (CAS 302806-11-7)
- 2-{[4-(difluoromethoxy)phenyl]formamido}acetic acid (CAS 304685-83-4)
- n-(4-(Difluoromethoxy)benzyl)-2-methoxyacetamide (CAS 1181529-92-9)
- n-(2-(Difluoromethoxy)benzyl)-2-methoxyacetamide (CAS 1211414-22-0)
- 4-(Difluoromethoxy)-3-isopropoxybenzamide (CAS 1574285-91-8)
- [5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methanol (CAS 946409-52-5)
- 2-(Difluoromethoxy)-6-ethoxyphenylpropanal (CAS 1804134-23-3)
Recommended Standards
- 1-Bromo-4-(tert-butylsulfanyl)benzene (CAS 25752-90-3)
- 2-Bromo-3-cyclohexylthiophene (CAS 241477-71-4)
- 1-(2,3,5,6-Tetrafluorobenzyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 895929-09-6)
- 3-Amino-3-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)propanoic acid hydrochloride (CAS 682804-57-5)
- N-(4-Piperidylmethyl)pyridin-2-amine (CAS 302338-97-2)
- 3-(3-Methyl-4-nitrophenoxy)pyrrolidine 4134AF 946760-47-0 C11H14N2O3 (CAS 946760-47-0)
- 2-((4-Chlorophenyl)sulfonyl)-1-(4-methoxyphenyl)ethan-1-one (CAS 61820-97-1)
- (3-Amino-pyrrolidin-1-yl)-acetic acid dihydrochloride (CAS 1187926-97-1)
- (S)-1-(5-Nitropyridin-2-yl)pyrrolidin-3-ol (CAS 1233859-93-2)
- N-(2-bromoethyl)-4-chlorobenzenesulfonamide (CAS 151389-59-2)
- 4-Ethyl-3-(3-methylthiophen-2-yl)-1h-pyrazol-5-amine (CAS 1187561-36-9)
- (4-Chlorophenyl)(3-(3-((2,4-dichlorobenzyl)oxy)phenyl)-1H-pyrazol-1-yl)methanone (CAS 477712-61-1)
- 4,6-Dimethyl-2-(piperidin-1-yl)-3-tosylpyridine (CAS 478245-31-7)
- D-allo-Thr5-Semaglutide (CAS CATO-C4X-2226243)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com