(4,4-Dimethyl-4,5-dihydro-thiazol-2-yl)-p-tolyl-amine CAS 565167-99-9
| CAS No. | 565167-99-9 |
| Molecular Formula | C12H16N2S |
| Molecular Weight | 220.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (4,4-Dimethyl-4,5-dihydro-thiazol-2-yl)-p-tolyl-amine (C12H16N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
(4,4-Dimethyl-4,5-dihydro-thiazol-2-yl)-p-tolyl-amine (CAS 565167-99-9), molecular formula C12H16N2S and molecular weight 220.33 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16N2S |
| Molecular Weight | 220.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dimethyl Standards
- Benzyl-(4,4-dimethyl-4,5-dihydro-thiazol-2-yl)-amine (CAS 125101-40-8)
- 2,2-Dimethyl-1-(2-(methylsulfonyl)ethyl)piperazine (CAS 1257293-61-0)
- (2,4-Dimethyl-phenyl)-(4-methyl-4,5-dihydro-thiazol-2-yl)-amine (CAS 519150-58-4)
- (2-[(1,2-Dimethyl-1h-indol-3-yl)thio]ethyl)amine (CAS 344334-46-9)
- (4,4-Dimethyl-4,5-dihydro-thiazol-2-yl)-o-tolyl-amine (CAS 438030-19-4)
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Recommended Standards
- (4-Ethyl-4,5-dihydro-thiazol-2-yl)-m-tolyl-amine (CAS 565167-96-6)
- (4-Ethyl-4,5-dihydro-thiazol-2-yl)-o-tolyl-amine (CAS 380349-31-5)
- (4-Ethyl-4,5-dihydro-thiazol-2-yl)-p-tolyl-amine (CAS 438030-87-6)
- 3-Methylene-4-(phenethylthio)tetrahydrofuran (CAS 192431-56-4)
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