2-Chloro-N-(4-(3,4-difluorophenyl)thiazol-2-yl)-2-phenylacetamide CAS 565192-28-1
| CAS No. | 565192-28-1 |
| Molecular Formula | C17H11ClF2N2OS |
| Molecular Weight | 364.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-N-(4-(3,4-difluorophenyl)thiazol-2-yl)-2-phenylacetamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Chloro-N-(4-(3,4-difluorophenyl)thiazol-2-yl)-2-phenylacetamide (CAS 565192-28-1), molecular formula C17H11ClF2N2OS and molecular weight 364.80 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Chloro-N-(4-(3,4-difluorophenyl)thiazol-2-yl)-2-phenylacetamide (C17H11ClF2N2OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 364.80 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H11ClF2N2OS |
| Molecular Weight | 364.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 5-(4-Cyanobenzamido)-2-ethoxybenzenesulfonyl chloride (CAS 680618-02-4)
- Allyl 4-((2-chloro-4-fluorobenzyl)oxy)-3-ethoxybenzoate (CAS 1706450-24-9)
- 3-[(4-chlorophenyl)methyl]aniline (CAS 1181603-39-3)
- (S)-Methyl 2,4-dimethyl-4-nitropentanoate (CAS 1897388-80-5)
- (2S)-2-{[1-(4-fluorobenzenesulfonyl)piperidin-3-yl]formamido}propanoic acid (CAS 956380-74-8)
- 2-Bromo-N-cyclohexyl-N,3-dimethylbutanamide (CAS 1016508-73-8)
- 1-tert-butyl-1H-pyrazol-5-amine hydrochloride (CAS 2031259-20-6)
- 3-(2,3,3-Trimethyl-3H-indol-5-yl)propanoic acid (CAS 1072069-91-0)
- Hydroxychloroquine Impurity 40 (CAS CATO-C4X-183540)
- 2-(4-Amino-1H-benzo[d]imidazol-1-yl)ethanol (CAS 102872-47-9)
- N-[(Tetrahydro-4-phenyl-2H-pyran-4-yl)methyl]acetamide (CAS 14006-33-8)
- Liraglutide Impurity 31 (CAS CATO-C4X-199231)
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