(3E)-1-[(2-Chlorophenyl)methyl]-3-[(4-fluorophenyl)imino]-2,3-dihydro-1H-indol-2-one CAS 478031-72-0
| CAS No. | 478031-72-0 |
| Molecular Formula | C21H14ClFN2O |
| Molecular Weight | 364.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3E)-1-[(2-Chlorophenyl)methyl]-3-[(4-fluorophenyl)imino]-2,3-dihydro-1H-indol-2-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(3E)-1-[(2-Chlorophenyl)methyl]-3-[(4-fluorophenyl)imino]-2,3-dihydro-1H-indol-2-one (CAS 478031-72-0), molecular formula C21H14ClFN2O and molecular weight 364.80 g/mol, is a CATO reference standard with documented purity and traceability.
(3E)-1-[(2-Chlorophenyl)methyl]-3-[(4-fluorophenyl)imino]-2,3-dihydro-1H-indol-2-one (C21H14ClFN2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3E)-1-[(2-Chlorophenyl)methyl]-3-[(4-fluorophenyl)imino]-2,3-dihydro-1H-indol-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H14ClFN2O |
| Molecular Weight | 364.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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