Dopamine Impurity 18 CAS 5663-56-9
| CAS No. | 5663-56-9 |
| Molecular Formula | C10H13NO3 |
| Molecular Weight | 195.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Dopamine Impurity 18 (CAS 5663-56-9, C10H13NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Dopamine Impurity 18 (C10H13NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 195.22 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dopamine Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13NO3 |
| Molecular Weight | 195.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Dopamine Standards
- Dopamine Impurity 63 (CAS 5663-55-8)
- Dopamine impurity 120 (CAS 3490-09-3)
- Dopamine Impurity 11 (CAS 22568-51-0)
- Dopamine Impurity 2 (CAS 39816-35-8)
- Dopamine Impurity 105 (CAS CATO-C4X-1908105)
- Dopamine Impurity 30 (CAS 339186-39-9)
- Dopamine Impurity 70 (CAS 528594-30-1)
- Dopamine Impurity 59 (CAS 6924-15-8)
Recommended Standards
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- Adrenaline Impurity 61 (CAS 31499-90-8)
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- Clevidipine Impurity 33 (CAS CATO-C4X-101533)
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