Ketoprofen EP Impurity H CAS 5689-33-8
| CAS No. | 5689-33-8 |
| Molecular Formula | C9H7NO2 |
| Molecular Weight | 161.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ketoprofen EP Impurity H.
As a process- or degradation-related impurity, Ketoprofen EP Impurity H (CAS 5689-33-8, C9H7NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ketoprofen EP Impurity H (C9H7NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ketoprofen EP Impurity H under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H7NO2 |
| Molecular Weight | 161.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Ketoprofen Standards
- Ketoprofen Impurity 13 (CAS 772-54-3)
- Ketoprofen Impurity 40 (CAS 28310-25-0)
- Ketoprofen Impurity 37 (CAS 18908-59-3)
- Ketoprofen Impurity 41 (CAS 68432-92-8)
- Ketoprofen Impurity 42 (CAS 76469-88-0)
- Ketoprofen EP Impurity G (CAS 5537-71-3)
- Ketoprofen Impurity 72 (CAS CATO-C4X-147172)
- Ketoprofen Impurity 62 (CAS 333991-43-8)
Recommended Standards
- Isavuconazole Impurity 58 (CAS 36776-32-6)
- Indacaterol Impurity 4 (CAS 15450-76-7)
- Ramosetron Impurity 10 (CAS 2058-74-4)
- Calcium Pantothenate EP Impurity F (CAS 505-47-5)
- Mianserin Impurity 107 (CAS CATO-C4X-1369107)
- Cinacalcet impurity 87 (CAS CATO-C4X-105987)
- Bicalutamide Impurity 19 (CAS 50986-83-9)
- 1-(2,4-Dichlorophenyl)-3,3-dimethylazetidin-2-one (CAS 280562-66-5)
- 4,4'-(5,6-Dimethylbenzo[c][1,2,5]thiadiazole-4,7-diyl)dibenzoic acid (CAS 2758181-33-6)
- 8-prop-1-ynyl-2,3-dihydro-1H-quinolin-4-one (CAS 2613135-52-5)
- 2-(Difluoromethyl)-5-fluoro-3-hydroxy-4-nitropyridine (CAS 1804425-06-6)
- 3,5-Bis(isopropyl)phenyl Diphenyl Phosphate (CAS 113765-39-2)
- (11R,12S)-Lactobacillic Acid (CAS 19625-10-6)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com