Ketoprofen Impurity 37 CAS 18908-59-3
| CAS No. | 18908-59-3 |
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ketoprofen Impurity 37 (CAS 18908-59-3), a pharmacopoeial impurity reference standard (molecular formula C10H9NO2, MW 175.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Ketoprofen Impurity 37 (C10H9NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ketoprofen Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Related Ketoprofen Standards
- Ketoprofen Impurity 40 (CAS 28310-25-0)
- Ketoprofen Impurity 41 (CAS 68432-92-8)
- Ketoprofen Impurity 42 (CAS 76469-88-0)
- Ketoprofen EP Impurity G (CAS 5537-71-3)
- Ketoprofen Impurity 72 (CAS CATO-C4X-147172)
- Ketoprofen Impurity 62 (CAS 333991-43-8)
- Ketoprofen Impurity 112 (CAS 42872-32-2)
- Ketoprofen Impurity 46 (CAS 713-36-0)
Recommended Standards
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- Celecoxib Impurity 66 (CAS CATO-C4X-104366)
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- Methyl 2-Chloro-4-(4-methyl-1-piperazinyl)benzoate (CAS 1059705-62-2)
- Folic Acid Impurity 35 (CAS 33157-07-2)
- (2,3-Difluorophenyl)(pyridin-2-yl)methanone (CAS 898780-15-9)
- Rac1 Inhibitor F56, control peptide (CAS 1315378-77-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com