Ethyl 4-amino-3-(4-bromophenyl)-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate CAS 57037-05-5
| CAS No. | 57037-05-5 |
| Molecular Formula | C12H11BrN2O2S2 |
| Molecular Weight | 359.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ethyl 4-amino-3-(4-bromophenyl)-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Ethyl 4-amino-3-(4-bromophenyl)-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate (CAS 57037-05-5), molecular formula C12H11BrN2O2S2 and molecular weight 359.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 4-amino-3-(4-bromophenyl)-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate (C12H11BrN2O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H11BrN2O2S2 |
| Molecular Weight | 359.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Ethyl Standards
- Ethyl 4-amino-3-(2-bromophenyl)-2-thioxo-2,3-dihydrothiazole-5-carboxylate (CAS 312922-22-8)
- 4-(1-(Boc-amino)cyclopropyl)phenylboronic Acid Pinacol Ester (CAS 1313441-88-1)
- Methyl 2-amino-5-((2,3-dichlorophenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 886657-53-0)
- N-(4-amino-2,6-dichlorophenyl)-4-(methylsulfonyl)benzamide (CAS 926207-01-4)
- 2-Amino-8-hydroxy-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one (CAS 85179-66-4)
- 1-Amino-4-((3-nitrophenyl)amino)anthracene-9,10-dione (CAS 88653-16-1)
- 2-amino-4-(5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)butanoic acid (CAS 52777-29-4)
- 2-Amino-4-(4-bromophenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile (CAS 220986-36-7)
Recommended Standards
- Methyl 5-(2-methoxy-2-oxoethyl)-1-[4-(trifluoromethoxy)phenyl]-1H-1,2,3-triazole-4-carboxylate (CAS 303995-98-4)
- Dimorpholino(phenyl)phosphine selenide (CAS 68580-22-3)
- N-(5-Bromo-2-methoxybenzyl)-2-(1H-indol-3-yl)ethanamine (CAS 331970-54-8)
- 4-(4-Benzylpiperazin-1-yl)-2-bromobenzaldehyde (CAS 883512-11-6)
- 1-(Difluoromethoxy)naphthalen-2-amine (CAS 1261661-36-2)
- 1-(oxan-4-yl)guanidine hydroiodide (CAS 1444183-64-5)
- (2E)-3-(4-Bromophenyl)-1-(2,5-dichlorophenyl)prop-2-en-1-one (CAS 1354807-90-1)
- (R)-1-(Hydroxymethyl)-2-methylenecyclopentan-1-ol (CAS 1186103-60-5)
- (1-Methyl-1H-imidazol-2-yl)(p-tolyl)methanamine hydrochloride (CAS 1216236-39-3)
- 1-Methoxy-4-methylisoquinoline-3-carbonyl chloride (CAS 89928-84-7)
- (1S)-2′-(1-Pyrrolidinylcarbonyl)[1,1′-binaphthalene]-2-carboxylic acid (CAS 2646621-96-5)
- 2-Fluoro-N-(3-methylbenzyl)benzamide (CAS 710318-32-4)
- 2-Amino-4-fluoropyridine (CAS 944401-77-8)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com