Palbociclib Impurity N82 CAS 571190-22-2

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.571190-22-2
Molecular FormulaC22H27N7O
Molecular Weight405.50 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Palbociclib Impurity N82 CAS 571190-22-2 chemical structure

Description

The occurrence of Palbociclib Impurity N82 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Palbociclib Impurity N82 (CAS 571190-22-2), a pharmacopoeial impurity reference standard (molecular formula C22H27N7O, MW 405.50 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Palbociclib Impurity N82 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 405.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Palbociclib Impurity N82 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC22H27N7O
Molecular Weight405.50 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Nitrogen Atoms7

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