Tiropramide Impurity B CAS 57227-08-4
| CAS No. | 57227-08-4 |
| Molecular Formula | C29H32N2O4 |
| Molecular Weight | 472.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tiropramide Impurity B.
CATO supplies Tiropramide Impurity B (CAS 57227-08-4), a pharmacopoeial impurity reference standard (molecular formula C29H32N2O4, MW 472.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Tiropramide Impurity B is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 472.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tiropramide Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H32N2O4 |
| Molecular Weight | 472.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 2 |
Related Tiropramide Standards
Recommended Standards
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- 2,11-Dithia[3.3]paracyclophane (CAS 28667-63-2)
- Dapoxetine Impurity 46 (CAS 524-42-5)
- (S)-2-((2-Aminoethyl)amino)-3-(1-propyl-1H-imidazol-4-yl)propanoic acid (CAS 400044-64-6)
- 3-((4-Chlorophenyl)carbamoyl)pyrazine-2-carboxylic acid (CAS 278610-25-6)
- (1-((4-Bromothiophen-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methanol (CAS 1248946-21-5)
- (Leu31,Pro34)-Peptide YY (human) trifluoroacetate salt (CAS 179986-95-9)
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