3-Chloro-[1,1'-biphenyl]-4-carboxylic acid CAS 5728-40-5
| CAS No. | 5728-40-5 |
| Molecular Formula | C13H9ClO2 |
| Molecular Weight | 232.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Chloro-[1,1'-biphenyl]-4-carboxylic acid (CAS 5728-40-5), molecular formula C13H9ClO2 and molecular weight 232.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Chloro-[1,1'-biphenyl]-4-carboxylic acid (C13H9ClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 3-Chloro-[1,1'-biphenyl]-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9ClO2 |
| Molecular Weight | 232.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 5-Chloro-3-phenylbenzoic acid (CAS 1082283-43-9)
- 7-chloro-4-oxo-chromene-2-carboxylic acid (CAS 114741-22-9)
- 3'-Chloro-4'-hydroxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 1176562-05-2)
- 5'-Chloro-2'-hydroxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 1181269-88-4)
- 5-Chloro-4-hydroxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 1248288-65-4)
- 3'-Chloro-5'-hydroxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 1261960-78-4)
- 3'-Chloro-2'-hydroxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 1263376-25-5)
- 2'-Chloro-[1,1'-biphenyl]-2-carboxylicacid (CAS 14498-95-4)
Recommended Standards
- 3'-Chloro-[1,1'-biphenyl]-4-carboxylic acid (CAS 5728-43-8)
- 3'-Chloro-3-hydroxy-[1,1'-biphenyl]-4-carbaldehyde (CAS 343603-99-6)
- 3-(3-Chlorophenoxy)benzaldehyde (CAS 78725-45-8)
- 3-Phenoxybenzoyl Chloride (CAS 3586-15-0)
- 5-Methyl-1-(4-nitrophenyl)-1H-pyrazole (CAS 13788-99-3)
- 6,8-Dichloro-3,4-dihydro-2H-benzo[b][1,4]oxazine hydrochloride (CAS 2722592-86-9)
- 2-Bromo-4-chloro-6-fluorobenzothiazole (CAS 210834-97-2)
- 1-Iodo-4-methoxybutane (CAS 20549-69-3)
- 2-Chloro-N'-(2,5-dichlorophenyl)pyridine-3-carbohydrazide (CAS 477864-50-9)
- 4-chloro-3-azatricyclo[6.2.1.0²⁷]undeca-2(7),3,5-triene-5-carbonitrile (CAS 1510965-06-6)
- 5-METHOXY-N-METHYLNAPHTHALEN-1-AMINE (CAS 61735-50-0)
- 2-BROMO-3-CHLOROPHENYLACETIC ACID (CAS 1261775-55-6)
- 4’-O-(b-D-2”,3”,4”,6”-Tetraacetyl-glucopyranosyl)-4-nitrophloretin (CAS 82628-87-3)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com