5-Ethoxy-3-methyl-1h-indole-2-carboxylic acid CAS 57291-56-2
| CAS No. | 57291-56-2 |
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Ethoxy-3-methyl-1h-indole-2-carboxylic acid (CAS 57291-56-2), a certified reference material (molecular formula C12H13NO3, MW 219.24 g/mol) for analytical method development and quality control.
The molecular framework of 5-Ethoxy-3-methyl-1h-indole-2-carboxylic acid (C12H13NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 5-Ethoxy-3-methyl-1h-indole-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 1 |
Related Ethoxy Standards
- 6-Ethoxy-1-methyl-1h-indole-2-carboxylic acid (CAS 1158494-69-9)
- 4-Ethoxy-1-methyl-1h-indole-2-carboxylic acid (CAS 1158604-52-4)
- 3-(3-Ethoxy-4-methoxyphenyl)-1H-1,2,4-triazole (CAS 1416340-49-2)
- 3-(4-Ethoxy-3-methoxyphenyl)-1H-1,2,4-triazole (CAS 1416343-95-7)
- 2-Ethoxy-4-(3-methyl-1H-1,2,4-triazol-5-yl)phenol (CAS 1416347-07-3)
- (3-Ethoxy-4,5-dihydroisoxazol-5-yl)(phenyl)methanone (CAS 155430-83-4)
- 1-(2-Ethoxy-7-methylpyrazolo[1,5-a]pyrimidin-6-yl)ethanone (CAS 159976-76-8)
- Methyl 4-ethoxy-1H-indole-2-carboxylate (CAS 185212-25-3)
Recommended Standards
- 5-Ethoxy-2-ethylisoindoline-1,3-dione (CAS 5140-54-5)
- 5-Ethoxy-4-methyl-3-phenyloxazol-2(3H)-one (CAS 494779-58-7)
- 5-Ethoxy-2-(4-methoxyphenyl)oxazole (CAS 477867-59-7)
- 5-Ethyl-1,7-dimethylpyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione (CAS 479579-10-7)
- Methyl 2-(Bromomethyl)-4-methoxybenzoate (CAS 15365-25-0)
- 2-((2-Chlorobenzyl)thio)-N,N-dimethyl-5,6,7,8-tetrahydroquinazolin-4-amine (CAS 478246-71-8)
- 5-Bromo-8-fluoro-4-hydroxyquinoline-3-carboxylic acid (CAS 1065093-65-3)
- 5-Acetyl-2-(4-fluorophenoxy)-6-methylpyridine-3-carbonitrile (CAS 303146-68-1)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)acetohydrazide (CAS 446276-13-7)
- [DPhe2] VIP, porcine (CAS 104051-15-2)
- (5-(Ethyl(methyl)amino)thiophen-2-yl)boronic acid (CAS 2225153-14-8)
- 4-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)piperidine (CAS 1225523-81-8)
- [(2R,3R,4R,5R)-5-bromo-3-tert-butoxycarbonyloxy-4-fluoro-4-methyl-tetrahydrofuran-2-yl]methyl tert-butyl carbonate (CAS 2761681-33-6)
- D-β-Asp15-Tirzepatide (CAS CATO-CPTD788930)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com