2-Methyl-6-(trifluoromethyl)-1H-indole CAS 57330-48-0
| CAS No. | 57330-48-0 |
| Molecular Formula | C10H8F3N |
| Molecular Weight | 199.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-Methyl-6-(trifluoromethyl)-1H-indole (CAS 57330-48-0), a certified reference material (molecular formula C10H8F3N, MW 199.17 g/mol) for analytical method development and quality control.
The molecular framework of 2-Methyl-6-(trifluoromethyl)-1H-indole (C10H8F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-Methyl-6-(trifluoromethyl)-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8F3N |
| Molecular Weight | 199.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 2-(2-Methyl-5-(trifluoromethyl)phenyl)acetonitrile (CAS 1000513-69-8)
- 2-(2-Methyl-3-(trifluoromethyl)phenyl)acetonitrile (CAS 1000515-00-3)
- 2-(4-Methyl-3-(trifluoromethyl)phenyl)acetonitrile (CAS 1000526-63-5)
- 3-Methyl-5-(trifluoromethyl)-1H-indole (CAS 1004547-95-8)
- 2-(5-Methyl-2-(trifluoromethyl)phenyl)acetonitrile (CAS 1017778-24-3)
- 2-Methyl-4-(trifluoromethyl)-1H-indole (CAS 1018971-85-1)
- 6-Methyl-2-(trifluoromethyl)-1H-indole (CAS 1067188-90-2)
- 2-(2-(Trifluoromethyl)phenyl)propanenitrile (CAS 1096308-46-1)
Recommended Standards
- 2-Methyl-5-(trifluoromethyl)-1H-indole (CAS 366448-74-0)
- 3-(3-(Trifluoromethyl)phenyl)propanenitrile (CAS 95096-06-3)
- 2,2,2-Trifluoroethyl diethylcarbamate (CAS 326-94-3)
- 3-(3-Hydrazinyl-5-oxo-2,5-dihydro-1,2,4-triazin-6-yl)propanoic acid (CAS 536728-03-7)
- 3-Amino-1-(2-(thiophen-3-yl)ethyl)pyridin-2(1h)-one (CAS 1343457-15-7)
- 7-Bromo-2-chloro-3-((2-(trimethylsilyl)ethoxy)methyl)quinazolin-4(3H)-one (CAS 2659373-00-7)
- (R)-Sulindac (CAS 190967-68-1)
- 3-Phenyl-3-(trifluoromethyl)diazirine (CAS 73899-14-6)
- 3,6-Dimethyl-4-(methylthio)pyridazine (CAS 865076-19-3)
- 2-(1h-1,2,4-Triazol-1-yl)phenol (CAS 1340463-49-1)
- 1-Methyl-4-{2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]ethyl}piperazine (CAS 1392419-83-8)
- 4-Hydrazinyl-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidine (CAS 40106-59-0)
- Tacrolimus Impurity 32 (CAS 129039-81-2)
- Semaglutide impurity 86 (CAS CATO-C4X-222686)
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