4-(3-Chlorophenyl)-N-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine CAS 574759-62-9
| CAS No. | 574759-62-9 |
| Molecular Formula | C17H11ClF3N3 |
| Molecular Weight | 349.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(3-Chlorophenyl)-N-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine (CAS 574759-62-9) is a high-purity analytical reference standard with the molecular formula C17H11ClF3N3 and a molecular weight of 349.74 g/mol.
Structurally, 4-(3-Chlorophenyl)-N-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine (C17H11ClF3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 349.74 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 4-(3-Chlorophenyl)-N-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H11ClF3N3 |
| Molecular Weight | 349.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- (E)-({5-[(4-chlorophenyl)sulfanyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl}methylidene)(methoxy)amine (CAS 321553-46-2)
- 5-((4-Chlorophenyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbonitrile (CAS 318239-39-3)
- 5-((3-Chlorophenyl)amino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CAS 1009820-21-6)
- N-(4-Chlorophenyl)-2-[2-(4-methoxyphenoxy)acetyl]-1-hydrazinecarboxamide (CAS 648915-34-8)
- N-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-2-naphthamide (CAS 921100-95-0)
- 2-(4-Chlorophenyl)-2-(4-(4-fluorobenzoyl)phenyl)acetonitrile (CAS 339114-45-3)
- 2-{[5-(4-chlorophenyl)-4-(furan-2-ylmethyl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 537017-56-4)
- 4-(4-Chlorophenyl)-2-phenylthiomorpholine-3,5-dione 1,1-dioxide (CAS 339109-49-8)
Recommended Standards
- 2-(6-Chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)ethyl 4-fluorobenzoate (CAS 866018-38-4)
- Midazolam Impurity 13 (CAS CATO-C4X-150913)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydro-2H-benzo[g]indazole (CAS 339101-40-5)
- Clodinafop Propargyl (CAS 105512-06-9)
- (6-Bromo-4-methylpyridin-3-yl)methanamine (CAS 1211585-93-1)
- 4-Chloro-1-fluoro-2-(2,2,2-trifluoroethyl)benzene (CAS 1099598-24-9)
- 1-(Quinolin-8-yl)hydrazin-1-ium chloride (CAS 73031-21-7)
- [4-(2-Chloroethyl)phenyl]methanol (CAS 1008517-68-7)
- 2-(Thiophen-3-yl)nicotinic acid (CAS 893723-60-9)
- Sulukast (CAS 98116-53-1)
- (+/-)-1-(4-FLUOROPHENYL)ETHYLAMINE (+/-)-4-FLUORO-ALPHA-METHYLBENZYLAMINE (RS)-1-(4-FLUOROPHENYL)ETHYLAMINE 1-(4'-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHAN-1-AMINE 1-(4-FLUOROPHENYL)ETHANAMINE 1-(4-FLUOROPHENYL)ETHYLAMINE 1-(P-FLUOROPHENYL)-ETHYLAMINE 2-AMINO-5-FLUOROTOLUENE 2-NITRO-5-FLUOROTOLUENE 3-FLUORO-6-AMINOTOLUENE 3-FLUORO-6-NITROTOLUENE 4-FLUORO-2-METHYL-1-NITROBENZENE 4-FLUORO-2-METHYL-PHENYLAMINE 4-FLUORO-2-METHYLBENZENAMINE 4-FLUORO-2-METHYLBENZENEAMINE 4-FLUORO-2-METHYLNITROBENZENE 4-FLUORO-A-METHYLBENZYLAMINE 4-FLUORO-ALPHA-METHYLBENZYLAMINE 4-FLUORO-O-TOLUIDINE 4-Fluoro-2-methylaniline 452-71-1 5-FLUORO-2-NITROTOLUENE AKOS BC-2617 AKOS P-2206693 AS04091 DL-4-FLUORO-ALPHA-METHYLBENZYLAMINE OTAVA-BB 7020293028 P-FLUORO-A-METHYLBENZYLAMINE P-FLUORO-ALPHA-METHYLBENZYLAMINE TIMTEC-BB SBB028217 (CAS 452-71-1)
- 1-(5-Amino-2-fluoro-4-hydroxyphenyl)ethan-1-one (CAS 1613720-25-4)
- 4-Borono-3,5-difluorobenzoic acid (CAS 1031857-98-3)
- Liraglutide Impurity 14 TFA Salt (CAS CATO-C4X-199214)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com