Midazolam Impurity 13 CAS CATO-C4X-150913
| CAS No. | CATO-C4X-150913 |
| Molecular Formula | C16H13ClFN3O3 |
| Molecular Weight | 349.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Midazolam Impurity 13 (CAS CATO-C4X-150913), a pharmacopoeial impurity reference standard (molecular formula C16H13ClFN3O3, MW 349.74 g/mol) used for the identification and quantification of trace impurities in APIs.
Midazolam Impurity 13 (C16H13ClFN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Midazolam Impurity 13 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H13ClFN3O3 |
| Molecular Weight | 349.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Midazolam Standards
- Midazolam EP Impurity I (CAS 112811-67-3)
- Midazolam Impurity 33 (CAS CATO-C4X-150933)
- Midazolam Impurity 32 (CAS CATO-C4X-150932)
- Midazolam 2-Oxide (CAS 59468-86-9)
- Midazolam Impurity 1 (CAS 59468-90-5)
- Midazolam EP Impurity D (CAS 59468-83-6)
- Midazolam Impurity 41 (CAS 59468-85-8)
- Midazolam Impurity 35 (CAS CATO-C4X-150935)
Recommended Standards
- 4-(3-Chlorophenyl)-N-[4-(trifluoromethyl)phenyl]pyrimidin-2-amine (CAS 574759-62-9)
- Clodinafop Propargyl (CAS 105512-06-9)
- 2-(6-Chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)ethyl 4-fluorobenzoate (CAS 866018-38-4)
- 3,4,5-Tribromo-1-nitro-1H-pyrazole (CAS 104599-40-8)
- Hexamidine Impurity 4 (CAS 74065-84-2)
- Valsartan impurity 7 (CAS 914465-68-2)
- Methylprednisolone impurity 88 (CAS CATO-C4X-191988)
- N-(4-chlorobenzyl)-6-(1H-pyrazol-1-yl)nicotinamide (CAS 321533-72-6)
- (4-Bromo-2-fluorophenyl)(cyclopentyl)methanol (CAS 1340449-20-8)
- 3-Phenyldodecane (CAS 2400-00-2)
- 2-(1-chloroethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (CAS 742118-88-3)
- Bis(8-methylnonyl) phenyl phosphite (CAS 25550-98-5)
- 1-(4-Benzoylpiperidino)-2-{4-[4-(trifluoromethyl)phenoxy]phenoxy}propan-1-one (CAS 260555-61-1)
- Antistasin-Related Peptide (CAS 161561-46-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com